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White matter architecture of the language network

  • Review Article
  • Published:
Translational Neuroscience

Abstract

The relevance of anatomical connectivity for understanding of the neural basis of language was recognized in the 19th century, and yet this topic has only recently become the subject of wider research interest. In this paper, I review recent findings on white matter tracts implicated in language: the arcuate fasciculus, superior longitudinal fasciculus, extreme capsule, uncinate fasciculus, middle longitudinal fasciculus, inferior longitudinal fasciculus, and inferior fronto-occipital fasciculus. The reviewed findings on these tracts were reported in studies that used a variety of methods, from post-mortem dissection and diffusion imaging to intraoperative electrostimulation with awake surgery patients. The emerging picture suggests that there is currently no consensus with regard to the exact number and identity of the tracts supporting language, their origins, trajectories, and terminations, as well as their functional interpretation.

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Abbreviations

AF:

arcuate fasciculus

BA:

Brodmann area

DTI:

diffusion tensor imaging

EC:

external capsule

EmC:

extreme capsule

IFG:

inferior frontal gyrus

IFOF:

inferior fronto-occipital fasciculus

ILF:

inferior longitudinal fasciculus

MdLF:

middle longitudinal fasciculus

MFG:

middle frontal gyrus

MRI:

magnetic resonance imaging

SFG:

superior frontal gyrus

SLF:

superior longitudinal fasciculus

STG:

superior temporal gyrus

STS:

superior temporal sulcus

UF:

uncinate fasciculus

WM:

white matter

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    Vanja Kljajevic

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Kljajevic, V. White matter architecture of the language network. Translat.Neurosci. 5, 239–252 (2014). https://doi.org/10.2478/s13380-014-0232-8

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  • DOI: https://doi.org/10.2478/s13380-014-0232-8

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