Abstract
The stereoselective synthesis of sulfamisterin I and its unnatural analogues II and V in their protected form was achieved through a common strategy. The Wittig reaction of aldehydes VIII and IX with the C14 hydrophobic side-chain X served as the key C-C connecting transformation. Subsequent functional group inter-conversions in the coupling products XI and XX completed the total synthesis.
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Špaková Raschmanová, J., Martinková, M., Gonda, J. et al. Stereoselective total synthesis of protected sulfamisterin and its analogues. Chem. Pap. 67, 1317–1329 (2013). https://doi.org/10.2478/s11696-013-0392-y
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DOI: https://doi.org/10.2478/s11696-013-0392-y