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An unusual cause of gastric extraluminal compression: fibrolamellar hepatocellular carcinoma

  • Case Report
  • Published:
Central European Journal of Medicine

Abstract

Fibrolamellar hepatocellular carcinoma (FLH) is a rare variant of hepatocellular carcinoma that typically occurs in adolescents or young subjects in an otherwise normal liver. Correct recognition of FLH is extremely important, because a complete resection of the tumor can confer an excellent prognosis. FLHs can become large, exerting mass effects on adjacent organs before diagnosis. Unfortunately, there are very few imaging reports describing external compression of the stomach caused by a FLH. We report the case of a young female suffering from dyspepsia and abdominal pain caused by stomach compression resulting from a large FLH.

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Abbreviations

FLH:

fibrolamellar hepatocellular carcinoma

HCC:

hepatocellular carcinoma

CT:

computerized tomography

References

  1. Craig J. R., Peters R.L., Edmondson H.A., Omata M., Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinicopathologic features, Cancer, 1980, 46, 372–379

    Article  PubMed  CAS  Google Scholar 

  2. Ichikawa T., Federle M.P., Grazioli L., Marsh W., Fibrolamellar hepatocellular carcinoma: pre- and posttherapy evaluation with CT and MR imaging, Radiology, 2000, 217, 145–151

    PubMed  CAS  Google Scholar 

  3. Ichikawa T., Federle M.P., Grazioli L., Madariaga J., Nalesnik M., Marsh W., Fibrolamellar hepatocellular carcinoma: imaging and pathologic findings in 31 recent cases, Radiology, 1999, 213, 352–361

    PubMed  CAS  Google Scholar 

  4. Berman M.A., Burnham J.A., Sheahan D.G., Fibrolamellar carcinoma of the liver: an immunohistochemical study of nineteen cases and a review of the literature, Hum. Pathol., 1988, 19, 784–794

    Article  PubMed  CAS  Google Scholar 

  5. Liu S., Chan K.W., Wang B., Qiao L., Fibrolamellar hepatocellular carcinoma, Am. J. Gastroenterol., 2009, 104, 2617–2624

    Article  PubMed  Google Scholar 

  6. Bosch F.X., Ribes J., Cléries R., Díaz M., Epidemiology of hepatocellular carcinoma, Clin. Liver Dis., 2005, 9, 191–211

    Article  PubMed  Google Scholar 

  7. Uccello M., Malaguarnera G., Pelligra E.M., Biondi A., Basile F., Motta M., Lipoprotein(a) as a potential marker of residual liver function in hepatocellular carcinoma, Indian J. Med. Paediatr. Oncol., 2011, 32, 71–75

    Article  PubMed  Google Scholar 

  8. Arista-Nasr J., Gutierrez-Villalobos L., Nuncio J., Maldonaldo H., Bornstein-Quevedo L., Fibrolamellar hepatocellular carcinoma in mexican patients, Pathol. Oncol. Res., 2002, 8, 133–137

    Article  PubMed  Google Scholar 

  9. Blachar A., Federle M.P., Ferris J.V., Lacomis J.M., Waltz J.S., Armfield D.R., et al., Radiologists’ performance in the diagnosis of liver tumors with central scars by using specific CT criteria, Radiology, 2002, 223, 532–539

    Article  PubMed  Google Scholar 

  10. Bogdanov M., Perisic M., Jurisic V., Stojacic-Djenic S., Kerkez M.M., Ultrasonographic examination of the liver circulation in patients with liver metastasis from colorectal cancer, J BUON, 2010, 15, 378–381

    PubMed  CAS  Google Scholar 

  11. Chen T.K., Wu C.H., Lee C.L., Lai Y.C., Yang S.S., Tu T.C., Endoscopic ultrasonography to study the causes of extragastric compression mimicking gastric submucosal tumor, J. Formos. Med. Assoc., 2001, 100, 758–761

    PubMed  CAS  Google Scholar 

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Correspondence to Mario Uccello.

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Dilettoso, S., Uccello, M., Dilettoso, A. et al. An unusual cause of gastric extraluminal compression: fibrolamellar hepatocellular carcinoma. cent.eur.j.med 8, 182–184 (2013). https://doi.org/10.2478/s11536-012-0096-7

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  • DOI: https://doi.org/10.2478/s11536-012-0096-7

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