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N-alkylation of ethylenediamine with alcohols catalyzed by CuO-NiO/γ-Al2O3

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Abstract

A simple method for N-alkylation of 1,2-diaminoethane with different alcohols in a fixed-bed reactor using cheap CuO-NiO/γ-Al2O3 as the catalyst has been developed. The present catalytic system was applicable in the N-alkylation of 1,2-diaminoethane with both primary and secondary alcohols. Mono-N-alkylation of 1,2-diaminoethane with low-carbon alcohols resulted in high yields; the yields of tetra-N-alkylation of 1,2-diaminoethane with low-carbon alcohols declined markedly with the increase of the molecular volume of alcohols.

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Authors and Affiliations

  1. Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, China

    Jia-Min Huang, Lu-Feng Xu, Chao Qian & Xin-Zhi Chen

  2. College of Chemical and Materials Engineering, Quzhou College, 324000, Quzhou, China

    Lu-Feng Xu

Authors
  1. Jia-Min Huang
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  2. Lu-Feng Xu
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  3. Chao Qian
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  4. Xin-Zhi Chen
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Correspondence to Xin-Zhi Chen.

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Huang, JM., Xu, LF., Qian, C. et al. N-alkylation of ethylenediamine with alcohols catalyzed by CuO-NiO/γ-Al2O3 . Chem. Pap. 66, 304–307 (2012). https://doi.org/10.2478/s11696-012-0140-8

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  • DOI: https://doi.org/10.2478/s11696-012-0140-8

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