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Laser immunotherapy

A novel treatment modality for metastatic tumors

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Abstract

Laser immunotherapy is a novel approach for the treatment of metastatic tumors. It combines a selective photothermal laser-tissue interaction for direct tumor destruction and an immunoadjuvant-directed simulation for immune responses. In experiments using a rat metastatic tumor model, laser immunotherapy resulted in the eradication of both treated primary tumors and untreated metastases at remote sites. It also induced anti-tumor resistance.

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Authors and Affiliations

  1. Biomedical Engineering Program, Department of Physics and Engineering, University of Central Oklahoma, 100 N. University Drive, 73034, Edmond, OK

    Wei R. Chen

  2. Department of Physics and Astronomy, University of Oklahoma, 73109, Norman, OK

    Wei R. Chen

  3. Wound Healing of Oklahoma, Inc., 3945 N. Walnut St., 73105, Oklahoma City, OK

    Raoul Carubelli & Robert E. Nordquist

  4. Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, 73109, Norman, OK

    Hong Liu

Authors
  1. Wei R. Chen
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  2. Raoul Carubelli
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  3. Hong Liu
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  4. Robert E. Nordquist
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Corresponding author

Correspondence to Wei R. Chen.

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Chen, W.R., Carubelli, R., Liu, H. et al. Laser immunotherapy. Mol Biotechnol 25, 37–43 (2003). https://doi.org/10.1385/MB:25:1:37

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  • DOI: https://doi.org/10.1385/MB:25:1:37

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