Skip to main content
SpringerLink
Log in

Hypopituitarism as a late complication of hemorrhagic fever

  • Original Articles
  • Published:
Endocrine Aims and scope Submit manuscript

Abstract

We report three patients who developed hypopituitarism as a late complication of hemorrhagic fever with renal syndrome (HFRS). Their past history, physical examination, and endocrine investigation confirmed hypopituitarism. Magnetic resonance imaging of the pituitary revealed atrophic pituitary gland with an empty sella. Hemorrhagic fever is endemic in certain regions of the Balkans, and this preliminary report suggests the importance of investigating the endocrine status in every patient who survived HFRS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Smadel, J. E. (1981). Am. J. Publ. Health. 43, 1327–1330.

    Google Scholar 

  2. Schmaljohn, C. S., Hasty, S. E., Dalrymple, J. M., et al. (1985). Science 227, 1041–1044.

    Article  PubMed  CAS  Google Scholar 

  3. Stuhlfauth, K. (1943). Dtsch. Med. Wochenschr. 69, 439–443.

    Article  Google Scholar 

  4. Heneberg, D., Vuksic, L., Lorelj, M., Lepes, I., Djordjevic, Z., and Mikes, M. (1962). Zbornik radova VMA 236, 71.

    Google Scholar 

  5. Zivaljevic, V., Adanja, B., Obradovic, M., and Lukac, V. (1995). Vojnosanit. Pregl. 52, 142–145.

    PubMed  CAS  Google Scholar 

  6. Jovanovic, D., Skataric, V., Kovacevic, Z., Maric, M., Gligic, A., and Romanovic, R. (1997). Vojnosanit. Pregl. 54, 453–458.

    PubMed  CAS  Google Scholar 

  7. Gligic, A., Stojanovic, R., Obradovic, M., et al. (1992). Eur. J. Epidemiol. 8, 816–825.

    Article  PubMed  CAS  Google Scholar 

  8. Lukac, V., Dokic, M., Rakovic-Savcic, L., et al. (1992). Vojnosanit. Pregl. 49, 201–205.

    PubMed  CAS  Google Scholar 

  9. Hukic, M., Kurt, A., Torstensson, S., Lundkvist, A., Wiger, D., and Niklasson, B. (1996). Lancet 347, 56–57.

    Article  PubMed  CAS  Google Scholar 

  10. Ciric, S., Denic, V., Mitrovic, V., Mitrovic-Perisic, N., Denic, N., and Ciric, S. (2003). Vojnosanit. Pregl. 60, 605–611.

    PubMed  Google Scholar 

  11. Klebanov, IuA. (1990). Klin. Med. (Mosk.) 68, 64–67.

    Google Scholar 

  12. Suh, D. C., Park, J. S., Park, S. K., Lee, H. K., and Chang, K. H. (1995). Am. J. Neuroradiol. 16, 175–178.

    PubMed  CAS  Google Scholar 

  13. Settergren, B., Boman, J., Linderholm, M., Wistrom, J., Hagg, E., and Arvidsson, P. A. (1992). Nephron 61, 234–235.

    Article  PubMed  CAS  Google Scholar 

  14. Hautala, T., Sironen, T., Vapalahti, O., et al. (2002). Clinical Infectious Disease 353, 96–101.

    Article  Google Scholar 

  15. Regal, M., Paramo, C., Sierra, S., and Garcia-Mayor, R. (2001). Clin. Endocrinol. (Oxf.) 55, 735–740.

    Article  CAS  Google Scholar 

  16. Simmonds, M. (1914). Dtch. Med. Wschr. 40, 322–323.

    Google Scholar 

  17. Sheehan, H. L. (1937). J. Path. Bact. 45, 189–214.

    Article  CAS  Google Scholar 

  18. Kovacs, K. (2003). Lancet 361, 520–522.

    Article  PubMed  Google Scholar 

  19. Hullinghorst, R. L. and Steer, A. (1953). Ann. Intern. Med. 38, 77–101.

    PubMed  CAS  Google Scholar 

  20. Lukes, R. J. (1952). Am. J. Med. 16, 639–650.

    Article  Google Scholar 

  21. Mayer, C. F. (1952). Lab. Invest. 1, 291–311.

    PubMed  CAS  Google Scholar 

  22. Valtonen, M., Kauppila, M., Kotilainen, P., et al. (1995). Scand. J. Infect. Dis. 237, 515–517.

    Google Scholar 

  23. Lee, H. W. and van der Groen, G. (1989). Prog. Med. Virol. 36, 62–102.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neuroendocrine Unit, Institute of Endocrinology, University Clinical Center, Dr Subotic 13, 11000, Belgrade, Serbia and Montenegro

    Sandra Pekic, Goran Cvijovic, Marko Stojanovic, Aleksandra Kendereski, Dragan Micic &  Vera Popovic MD, PhD, FRCP

Authors
  1. Sandra Pekic
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Goran Cvijovic
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marko Stojanovic
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Aleksandra Kendereski
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Dragan Micic
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Vera Popovic MD, PhD, FRCP
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vera Popovic MD, PhD, FRCP.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pekic, S., Cvijovic, G., Stojanovic, M. et al. Hypopituitarism as a late complication of hemorrhagic fever. Endocr 26, 79–82 (2005). https://doi.org/10.1385/ENDO:26:2:079

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1385/ENDO:26:2:079

Key Words

Search

Navigation