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Reasons for Re-Excision After Lumpectomy for Breast Cancer: Insight from the American Society of Breast Surgeons MasterySM Database

  • Breast Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

There is marked variability of re-excision rates after initial lumpectomy for breast cancer. Reasons for re-excision and variability across surgeons have not been well documented. We hypothesized the American Society of Breast Surgeons (ASBrS) MasterySM Program can identify reasons for re-excision.

Methods

Data from January 1 to 7 November 2013 were evaluated in the ASBrS MasterySM Program to determine re-excision lumpectomy rate (RELR). On 1 June 2013, a tool to track reasons for re-excision was developed. Variation in re-excision rate by surgeon and patient characteristics was performed by Chi square test and Fisher’s test for univariate analysis, then logistic regression with backwards elimination method for multivariate analysis.

Results

For 6,725 patients undergoing initial lumpectomy for cancer, 328 surgeons reported 1,451 (21.6 %) patients had one or more re-excisions. The most common reasons for re-excision were ink positive margins in 783 (49.7 %), margin <1 mm (34.3 %), and margin 1–2 mm (7.2 %). By multivariate analysis, re-excision rates were lower in patients aged less than 35 years, with White (non-) Hispanic ethnicity, and, among surgeons in solo practice, more years in practice and higher-volume practice.

Conclusion

Half of re-excisions after initial lumpectomy were performed for margins that are positive. Most of the remainder were for negative close (<1–2 mm) margins. This information corroborates surgeon survey data regarding reasons for re-excision and provides proof of concept the MasterySM Program can capture surgical outcome data in real time, providing opportunity and a method for future performance improvement.

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Acknowledgment

The authors acknowledge the Gundersen Medical Foundation and the Norma J. Vinger Center for Breast Care endowment for statistical support, Choua Amee Vang for assistance in manuscript preparation, Ben and Margaret Schlosnagel for MasterySM technical support, and the entire administrative staff and executive officers of the American Society of Breast Surgeons for allowing access to the MasterySM registry for research.

Disclosures

Jeffrey Landercasper, Amy C. Degnim, and Mohammed Al-Hamadani have no disclosures to declare. Eric Whitacre is a speaker for and has received speaker fees from Myriad Genetics.

Author information

Authors and Affiliations

  1. Department of Surgery, Gundersen Health System, La Crosse, WI, USA

    Jeffrey Landercasper MD

  2. Norma J. Vinger Center for Breast Care, Gundersen Health System, La Crosse, WI, USA

    Jeffrey Landercasper MD

  3. Breast Center of Southern Arizona, Tucson, AZ, USA

    Eric Whitacre MD

  4. Department of Surgery, Mayo Clinic, Rochester, MN, USA

    Amy C. Degnim MD

  5. Department of Medical Research, Gundersen Health System, La Crosse, WI, USA

    Mohammed Al-Hamadani MBChB, MPH

Authors
  1. Jeffrey Landercasper MD
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  2. Eric Whitacre MD
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  3. Amy C. Degnim MD
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  4. Mohammed Al-Hamadani MBChB, MPH
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Correspondence to Jeffrey Landercasper MD.

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Landercasper, J., Whitacre, E., Degnim, A.C. et al. Reasons for Re-Excision After Lumpectomy for Breast Cancer: Insight from the American Society of Breast Surgeons MasterySM Database. Ann Surg Oncol 21, 3185–3191 (2014). https://doi.org/10.1245/s10434-014-3905-1

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  • DOI: https://doi.org/10.1245/s10434-014-3905-1

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