Skip to main content
Log in

Supercritical Fluid Treatment of Three-Dimensional Hydrogel Matrices Obtained from Allylchitosan by Laser Stereolithography

  • Published:
Russian Journal of Physical Chemistry B Aims and scope Submit manuscript

Abstract

The effect of the treatment of hydrogel matrices based on allyl-substituted chitosans and formed by laser stereolithography in supercritical carbon dioxide (SC-CO2) on their surface polarity and mechanical characteristics was studied. Treatment in a flow mode increased the mechanical stability of the materials due to the effective extraction of the low-molecular components and oligomers. The surface polarity of the matrix decreased, improving its biocompatibility. The hydrogel matrices treated in SC-CO2 have no cytotoxic activity, due to which they can be used in tissue engineering.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. T. Billiet, M. Vandenhaute, J. Schelfhout, S. van Vlierberghe, and P. Dubruel, Biomaterials 33, 6020 (2012).

    Article  CAS  PubMed  Google Scholar 

  2. A. Koroleva, O. Kufelt, S. Schlie-Wolter, U. Hinze, and B. Chichkov, Biomed. Tech. 58, 399 (2013).

    Article  CAS  Google Scholar 

  3. F. Croisier and C. Jérôme, Eur. Polym. J. 49, 780 (2013).

    Article  CAS  Google Scholar 

  4. O. Kufelt, A. El-Tamer, C. Sehring, M. Meaner, S. Schlie-Wolter, and B. N. Chichkov, Acta Biomater. 18, 186 (2015).

    Article  CAS  PubMed  Google Scholar 

  5. A. Atala and J. J. Yoo, Essentials of 3D Biofabrication and Translation (Academic, New York, 2015).

    Google Scholar 

  6. L. N. Nikitin, M. O. Gallyamov, E. E. Said-Galiev, A. R. Khokhlov, and V. M. Buznik, Zh. Ros. Khim. Ob-Va Im. D. I. Mendeleeva 52 (3), 56 (2008).

    CAS  Google Scholar 

  7. V. P. Costa, M. E. M. Braga, C. M. M. Duarte, C. Alvarez-Lorenzo, A. Concheiro, M. H. Gil, and H. C. de Sousa, J. Supercrit. Fluids 53, 65 (2010).

    Article  CAS  Google Scholar 

  8. T. A. Akopova, P. S. Timashev, T. S. Demina, K. N. Bardakova, N. V. Minaev, V. F. Burdukovskii, G. V. Cherkaev, L. V. Vladimirov, A. V. Istomin, E. A. Svidchenko, N. M. Surin, and V. N. Bagratashvili, Mendeleev Commun. 25, 280 (2015).

    Article  CAS  Google Scholar 

  9. T. A. Akopova, A. V. Istomin, M. A. Khavpachev, T.S.Demina, E. A. Svidchenko, G. V. Cherkaev, N. M. Surin, and A. N. Zelenetskii, Izv. Ufim. Nauch. Tsentra RAN 1 (3), 5 (2016).

    Google Scholar 

  10. P. S. Timashev, K. N. Bardakova, S. N. Churbanov, L. I. Krotova, A. M. Grigor’ev, M. M. Novikov, S. G. Lakeev, V. I. Sevast’yanov, and V. N. Bagratashvili, Vestn. Transplantol. Iskusstv. Organov 18 (3), 85 (2016).

    Google Scholar 

  11. P. S. Timashev, K. N. Bardakova, T. S. Demina, G. I. Pudovkina, M. M. Novikov, M. A. Markov, D.S.Asyutin, L. F. Pimenova, E. A. Svidchenko, A.M. Ermakov, I. I. Selezneva, V. K. Popov, N. A. Konovalov, T. A. Akopova, A. B. Solov’eva, V. Ya. Panchenko, and V. N. Bagratashvili, Sovrem. Tekhnol. Med. 7 (3), 20 (2015).

    Article  Google Scholar 

  12. E. Breel, Tech. Report No. AN1501 (2015).

    Google Scholar 

  13. A. Moerman, Master (Biomed. Eng.) Thesis (2015).

    Google Scholar 

  14. Y. Yuan and T. R. Lee, Surf. Sci. Tech. 51, 3 (2013).

    Article  CAS  Google Scholar 

  15. C. Rulison, KRUSS Application Note AN213 (2000), p. 1.

    Google Scholar 

  16. R. Rogowska, Maint. Probl. 2, 193 (2006).

    Google Scholar 

  17. V. Repeta, Acta Graph. 24 (3–4), 79 (2013).

    Google Scholar 

  18. GOST (State Standard) R ISO 10993-5-2009, Part 5.

  19. P. S. Timashev, K. N. Bardakova, T. S. Demina, G. I. Pudovkina, M. M. Novikov, M. A. Markov, D. S. Asyutin, L. F. Pimenova, E. A. Svidchenko, A. M. Ermakov, I. I. Selezneva, V. Popov, N. Konovalov, T. A. Akopova, A. B. Solovieva, et al., Mod.Technol. Med. 7, 20 (2015).

    Google Scholar 

  20. L. C. Xu, J. W. Bauer, and C. A. Siedlecki, Colloids Surf., B 124, 49 (2014).

    Article  CAS  Google Scholar 

  21. H. Liao, D. Munoz-Pinto, X. Qu, Y. Hou, M. A. Grunlan, and M. S. Hahn, Acta Biomater. 4, 1161 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. E. Lazhko.

Additional information

Original Russian Text © A.E. Lazhko, K.N. Bardakova, B.S. Shavkuta, S.N. Churbanov, M.A. Markov, T.A. Akopova, O.O. Parenago, A.M. Grigoryev, P.S. Timashev, V.V. Lunin, V.N. Bagratashvili, 2017, published in Sverkhkriticheskie Flyuidy. Teoriya i Praktika, 2017, Vol. 12, No. 3, pp. 70–81.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lazhko, A.E., Bardakova, K.N., Shavkuta, B.S. et al. Supercritical Fluid Treatment of Three-Dimensional Hydrogel Matrices Obtained from Allylchitosan by Laser Stereolithography. Russ. J. Phys. Chem. B 12, 1144–1151 (2018). https://doi.org/10.1134/S1990793118070072

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1990793118070072

Keywords

Navigation