Abstract
The possibility of sterilization of porous ultrahigh-molecular-weight polyethylene in subcritical Freons R22 and R410a in the absence of modifiers is for the first time demonstrated. The maximum sterilization effect is achieved when sterilization with Freon R410a is performed in static conditions for 30 min at 50°С and 250 bar or with Freon R22 for 60 min at 70°С and cyclically varied pressure within 100–290 bar (press–depress mode).
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References
S. Qu, A. Liu, X. Liu, Y. Bai, and J. Weng, Appl. Surf. Sci. 262, 168 (2012).
M. P. Fernandez-Ronco, J. Kluge, J. Krieg, S. Rodrigez-Rojo, B. Andreatta, R. Luginbuehl, M. Mazzotti, and J. Sague, J. Supercrit. Fluids 95, 204 (2014).
P. S. Rama-Sreekanth and S. Kanagarai, J. Mech. Behavior Biomed. Mater. 21, 57 (2013).
A. Simmons, in Sterilisation of Biomaterials and Medical Devices, Woodhead Publishing Series in Biomaterials, Ed. by S. Lerouge and A. Simmons (Woodhead, London, 2012), p. 310.
A. Jimenez, G. L. Thompson, M. A. Matthews, T. A. Davis, K. Crocker, J. S. Lyons, and A. Trapotsis, J. Supercrit. Fluids 42, 366 (2007).
J. Fages, A. Marty, C. Delga, J. S. Condoret, D. Combes, and P. Frayssinet, Biomaterials 15, 650 (1994).
J. Zhang, T. A. Davis, M. A. Matthews, M. J. Drews, M. LaBerge, and Y. H. An, J. Supercrit. Fluids 38, 354 (2006).
A. White, D. Burns, and T. W. Christensen, J. Biotechnol. 123, 504 (2006).
M. Perrut, J. Supercrit. Fluids 66, 359 (2012).
S. Lanzalaco, S. Campora, F. C. Pavia, E. R. di Leonardo, G. Ghersi, O. Scialdone, et al., in Proceedings of the 2nd International Conference on Bioinspired and Biobased Chemistry and Materials, Nice, France, October 15–17, 2014.
A. Jimenez, J. Zhang, and M. A. Matthews, Biotechnol. Bioeng. 101, 1344 (2008).
M. Meyer, I. Prade, R. Leppchen-Fröhlich, A. Felix, V. Herdegen, R. Haseneder, and J.-U. Repke, J. Supercrit. Fluids 102, 32 (2015).
US Patent 8007718 B1 (2011).
J. M. Silva, A. A. Rigo, I. A. Dalmolin, I. Debien, R. L. Cansian, J. V. Oliveira, and M. A. Mazutti, Food Control 29, 76 (2013).
F. S. Senatov, A. N. Kopylov, N. Yu. Anisimova, M. V. Kiselevsky, and A. V. Maksimkin, Mater. Sci. Eng. C 48, 566 (2015).
J. L. Ellis, J. C. Titone, D. L. Tomasko, N. Annabi, and F. Dehyghani, J. Supercrit. Fluids 52, 235 (2010).
M. J. Alfa, P. DeGagne, N. Olson, and T. Puchalski, Infect. Control Hosp. Epidemiol. 17, 92 (1996).
M. J. Alfa, Canada Commun. Disease Rep. 21 (9), F–3 (1995).
V. A. Kamachev, A. Yu. Shadrin, A. A. Murzin, and D. N. Shafikov, Sverkhkrit. Fluidy Teor. Prakt. 2 (3), 48 (2007).
A. V. Maksimkin, S. D. Kaloshkin, V. V. Cherdyntsev, D. I. Chukov, and A. A. Stepashkin, Med. Tekh. 278 (2), 16 (2013).
D. Yu. Zalepugin, A. V. Maksimkin, N. A. Tilkunova, I. V. Chernyshova, F. S. Senatov, and M. I. Vlasov, Russ. J. Phys. Chem. B 9, 1157 (2015).
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Original Russian Text © D.Yu. Zalepugin, A.V. Maksimkin, M.V. Kiselevsky, N.A. Tilkunova, N.Yu. Anisimova, I.V. Chernysheva, F.S. Senatov, M.I. Vlasov, 2016, published in Sverkhkriticheskie Flyuidy. Teoriya i Praktika, 2016, Vol. 11, No. 1, pp. 84–91.
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Zalepugin, D.Y., Maksimkin, A.V., Kiselevsky, M.V. et al. Sterilization of a porous ultrahigh-molecular-weight polyethylene in supercritical Freons. Russ. J. Phys. Chem. B 10, 1264–1268 (2016). https://doi.org/10.1134/S1990793116080170
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DOI: https://doi.org/10.1134/S1990793116080170