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Synthesis of heterocycles based on arylation products of unsaturated compounds: XVII. Arylation of 2-acetylfuran and synthesis of 3-R-6-(5-aryl-2-furyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines

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Abstract

Reaction of 2-acetylfuran with arenediazonium chlorides under Meerwein reaction conditions led to the formation of 5-aryl-2-acetylfurans. The bromination of these compounds gave 2-bromo-1-(5-aryl-2-furyl)-ethanones that reacted with 4-amino-4H-5-R-1,2,4-triazole-3-thiols to form 3-R-6-(5-aryl-2-furyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines.

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Authors and Affiliations

  1. Ivan Franko Lvov National University, Lvov, 79005, Ukraine

    N. D. Obushak, Yu. I. Gorak, V. S. Matiichuk & R. Z. Lytvyn

Authors
  1. N. D. Obushak
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  2. Yu. I. Gorak
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  3. V. S. Matiichuk
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  4. R. Z. Lytvyn
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Correspondence to N. D. Obushak.

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Original Russian Text © N.D. Obushak, Yu.I. Gorak, V.S. Matiichuk, R.Z. Lytvyn, 2008, published in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 11, pp. 1712–1716.

For communcation XVI, see [1].

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Obushak, N.D., Gorak, Y.I., Matiichuk, V.S. et al. Synthesis of heterocycles based on arylation products of unsaturated compounds: XVII. Arylation of 2-acetylfuran and synthesis of 3-R-6-(5-aryl-2-furyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines. Russ J Org Chem 44, 1689–1694 (2008). https://doi.org/10.1134/S1070428008110213

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  • DOI: https://doi.org/10.1134/S1070428008110213

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