Abstract
Synthetic routes to new amino nitriles with the functional groups at the 2-position of the adamantane core, based on reactions of adamantanonimines with acetone cyanohydrin or of adamantanone cyanohydrin with aliphatic amines, are considered. The products can be used for preparing new biologically active substances, unsymmetrical adamantyl-containing diamines or amino acids.
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Original Russian Text © Yu.V. Popov, V.M. Mokhov, N.A. Tankabekyan, O.Yu. Safronova, 2012, published in Zhurnal Prikladnoi Khimii, 2012, Vol. 85, No. 9, pp. 1474–1481.
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Popov, Y.V., Mokhov, V.M., Tankabekyan, N.A. et al. Synthesis of 2-amino-2-cyanoadamantane and its derivatives. Russ J Appl Chem 85, 1387–1394 (2012). https://doi.org/10.1134/S1070427212090145
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DOI: https://doi.org/10.1134/S1070427212090145