Abstract
The results of studies of the molecular action mechanism of the peptides Semax and Selank—simple glyprolines that are used to prepare peptide-based drugs—are presented. A concept of creating an amino acid sequence of peptides is given; their interaction with receptor systems of the cell and their influence on the cell’s transcriptome, which forms the cell-mediated response, are considered. On the basis of the findings, pharmaceutical compositions of peptide drugs have been developed and their production and introduction into clinical practice have been organized.
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Original Russian Text © N.F. Myasoedov, 2016, published in Vestnik Rossiiskoi Akademii Nauk, 2016, Vol. 86, No. 6, pp. 488–494.
RAS Academician Nikolai Fedorovich Myasoedov is a deputy director of the RAS Institute of Molecular Genetics.
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Myasoedov, N.F. Innovative drugs: From basic research to production. Her. Russ. Acad. Sci. 86, 151–157 (2016). https://doi.org/10.1134/S1019331616030084
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DOI: https://doi.org/10.1134/S1019331616030084