Skip to main content
SpringerLink
Log in

Comparative characteristics of the gene pool of Teleuts inferred from Y-chromosomal marker data

  • Human Genetics
  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

The gene pool structure of Teleuts was examined and Y-chromosomal haplogroups composition and frequencies were determined. In the gene pool of Teleuts, five haplogroups, C3×M77, N3a, R1b*, R1b3, and R1a1, were identified. Evaluation of the genetic differentiation of the samples examined using analysis of molecular variance (AMOVA) with two marker systems (frequencies of haplogroups and Y-chromosomal microsatellite haplotypes) showed that Bachat Teleuts were equally distant from Southern and Northern Altaians. In Siberian populations, the frequencies and molecular phylogeny of the YSTR haplotypes within Y-chromosomal haplogroup R1a1 were examined. It was demonstrated that Teleuts and Southern Altaians had very close and overlapping profiles of R1a1 haplotypes. Population cluster analysis of the R1a1 YSTR haplotypes showed that Teleuts and Southern Altaians were closer to one another than to all remaining Siberian ethnic groups. Phylogenetic analysis of N3a haplotypes suggested specificity of Teleut haplotypes and their closeness to those of Tomsk Tatars. Teleuts were characterized by extremely high frequency of haplogroup R1b*, distinguished for highly specific profile of YSTR haplotypes and high haplotype diversity. The results of the comparative analysis suggested that the gene pool of Bachat Teleuts was formed on the basis of at least two heterogeneous genetic components, probably associated with ancient Turkic and Samoyedic ethnic components.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Potapov, L.P., Ocherki po istorii altaitsev (Essays on the History of Altaians), Moscow: Akad. Nauk SSSR, 1953.

    Google Scholar 

  2. Potapov, L.P., Etnicheskii sostav i proiskhozhdenie altaitsev (Ethnic Composition and the Origin of Altaians), Leningrad: Nauka, 1969.

    Google Scholar 

  3. Lotosh, E.A., Kolbasko, A.V., Dranishnikov, A.K., et al., Population, Medical, and Genetic Characteristic of Indigenous People of Altai Mountains, Vestn. Akad. Med. Nauk SSSR, 1984, no. 7, pp. 78–81.

  4. Luzina, F.A., Hereditary Polymorphism and Genetic Processes in Indigenous Population of Altai Mountains, Extended Abstract of Cand. Sci. (Biol.) Dissertation, Moscow State Univ., Moscow, 1987, p. 17.

    Google Scholar 

  5. Luzina, F.A. and Lotosh, O.E., Differentiation and Inbreeding among Teleuts at Quasigenetic Markers, in Gigiena, organizatsiya zdravookhraneniya i profpatologiya (Hygiene, Public Health Service Management, and Occupational Therapy), Proc. XL Interregional Scientific Practical Conf. with Int. Participation, Novokuznetsk, 2005, vol. 1, pp. 160–165.

  6. Johns, M.B. and Pauls-Thomas, J.E., Purification of Human Genomic DNA from Whole Blood Using Sodium Perchlorate in Place of Phenol, Anal. Biochem., 1989, vol. 180, pp. 276–278.

    Article  PubMed  CAS  Google Scholar 

  7. The Y Chromosome Consortium, A Nomenclature System for the Tree of Human Y-Chromosomal Binary Haplogroups, Genome. Res., 2002, vol. 12, pp. 339–348.

  8. Kharkov, V.N, Stepanov, V.A., Borinskaya, S.A., et al., Gene Pool Structure of Eastern Ukrainians as Inferred from the Y-Chromosome Haplogroups, Russ. J. Genet., 2004, vol. 40, no. 3, pp. 326–331.

    Article  CAS  Google Scholar 

  9. Kharkov, V.N., Stepanov, V.A., Feshchenko, S.P., et al., Frequencies of Y Chromosome Binary Haplogroups in Belarusians, Russ. J. Genet., 2005, vol. 41, no. 8, pp. 928–931.

    Article  CAS  Google Scholar 

  10. Kharkov, V.N., Stepanov, V.A., Medvedeva, O.F., et al., Gene Pool Differences between Northern and Sothern Altaians Inferred from Y-Chromosomal Haplogroups, Russ. J. Genet., 2007, vol. 43, no. 5, pp. 675–687.

    Article  CAS  Google Scholar 

  11. Stepanov, V.A. and Puzyrev, V.P., Analysis of the Allele Frequencies of Seven Y-Chromosome Microsatellite Loci in Three Tuvinian Populations, Russ. J. Genet., 2000, vol. 36, no. 2, pp. 179–185.

    CAS  Google Scholar 

  12. Stepanov, V.A. and Puzyrev, V.P., Y-Chromosome Microsatellite Haplotypes Demonstrate Absence of Subdivision and Presence of Several Components in the Tuvinian Male Gene Pool, Russ. J. Genet., 2000, vol. 36, no. 3, pp. 298–304.

    CAS  Google Scholar 

  13. Kayser, M., Krawczak, M., and Excoffier, L., An Extensive Analysis of Y-Chromosomal Microsatellite Haplotypes in Globally Dispersed Human Populations, Am. J. Hum. Genet., 2001, vol. 68, pp. 990–1018.

    Article  PubMed  CAS  Google Scholar 

  14. Kayser, M., Kittler, R., Erler, A., et al., A Comprehensive Survey of Human Y-Chromosomal Microsatellites, Am. J. Hum. Genet., 2004, vol. 74, pp. 1183–1197.

    Article  PubMed  CAS  Google Scholar 

  15. Kim, J.O. and Mueller, C.W., Factor Analysis: Statistical Methods and Practical Issues, no. 07-014 of Sage University Paper Series on Quantitative Applications in the Social Sciences, Sage: Newbury Park, 1978.

    Google Scholar 

  16. Nei, M., Molecular Evolutionary Genetics, New York: Columbia Univ. Press, 1987.

    Google Scholar 

  17. Excoffier, L., Smouse, P., and Quattro, J., Analysis of Molecular Variance Inferred from Metric Distances among DNA Haplotypes: Application to Human Mitochondrial DNA Restriction Data, Genetics, 1992, vol. 131, pp. 479–491.

    PubMed  CAS  Google Scholar 

  18. Schneider, S., Roessli, D., and Excoffier, L., Arlequin, Version 2.000: A Software for Population Genetics Data Analysis, 2000.

  19. Bandelt, H.-J., Forster, P., and Rohl, A., Median-Joining Networks for Inferring Intraspecific Phylogenies, Mol. Biol. Evol., 1999, vol. 16, pp. 37–48.

    PubMed  CAS  Google Scholar 

  20. Bandelt, H.-J., Forster, P., Sykes, B.C., and Richards, M.B., Mitochondrial Portraits of Human Populations Using Median Networks, Genetics, 1995, vol. 141, pp. 743–753.

    PubMed  CAS  Google Scholar 

  21. Saitou, N. and Nei, M., The Neighbour-Joining Method: A New Method for Reconstructing Phylogenetic Trees, Mol. Biol. Evol., 1987, vol. 4, pp. 406–425.

    PubMed  CAS  Google Scholar 

  22. Felsenstein, J., PHYLIP, Version 3.5, Washington, DC: Seattle Univ., 1993.

    Google Scholar 

  23. Derenko, M.V., Malyarchuk, B.A., Denisova, G.A., et al., Contrasting Patterns of Y-Chromosome Variation in South Siberian Populations from Baikal and Altai-Sayan Regions, Hum. Genet., 2006, vol. 118, pp. 591–604.

    Article  PubMed  Google Scholar 

  24. Cinnioglu C., King R., Kivisild T. et al. Excavating Y-Chromosome Haplotype Strata in Anatolia, Hum. Genet., 2004, vol. 114, pp. 127–148.

    Article  PubMed  Google Scholar 

  25. Sengapta, S., Zhivotovsky, L., King, R., et al., Polarity and Temporality of High-Resolution Y-Chromosome Distributions in India Identify Both Indigenous and Exogenous Expansions and Reveal Minor Genetic Influence of Central Asian Pastoralists, Am. J. Hum. Genet., 2006, vol. 78, pp. 202–221.

    Article  Google Scholar 

  26. Zerjal, T., Xue, Y., Bertorelle, G., et al., The Genetic Legacy of the Mongols, Am. J. Hum. Genet., 2006, vol. 72, pp. 717–721.

    Article  Google Scholar 

  27. Bat’yanova, E.P., Towards Ethnopolitical Situation in Kemerovo Oblast, in Issledovaniya po prikladnoi i neotlozhnoi etnologii (Studies on Applied and Urgent Ethnology), Moscow: IEA RAN, 1993.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Medical Genetics, Tomsk Scientific Center, Russian Academy of Medical Sciences, Tomsk, 63050, Russia

    V. N. Kharkov, O. F. Medvedeva, V. P. Puzyrev & V. A. Stepanov

  2. Research Institute for Complex Problems of Hygiene and Occupational Diseases, Russian Academy of Medical Sciences, Novokuznetsk, 654041, Russia

    F. A. Luzina & N. I. Gafarov

  3. Novokuznetsk Institute of Continuing Medical Education, Novokuznetsk, 654005, Russia

    A. V. Kolbasko

Authors
  1. V. N. Kharkov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. F. Medvedeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. A. Luzina
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. V. Kolbasko
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. N. I. Gafarov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. V. P. Puzyrev
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. V. A. Stepanov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. N. Kharkov.

Additional information

Original Russian Text © V.N. Kharkov, O.F. Medvedeva, F.A. Luzina, A.V. Kolbasko, N.I. Gafarov, V.P. Puzyrev, V.A. Stepanov, 2009, published in Genetika, 2009, Vol. 45, No. 8, pp. 1132–1142.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kharkov, V.N., Medvedeva, O.F., Luzina, F.A. et al. Comparative characteristics of the gene pool of Teleuts inferred from Y-chromosomal marker data. Russ J Genet 45, 994–1003 (2009). https://doi.org/10.1134/S1022795409080158

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1022795409080158

Keywords

Search

Navigation