Mutant p53: from guardian to fallen angel?

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Di Agostino S, Strano S, Emiliozzi V, Zerbini V, Mottolese M, Sacchi A et al. (2006). Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation. Cancer Cell 10: 191–202.
Article CAS Google Scholar
Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M et al. (1993). Gain of function mutations in p53. Nat Genet 4: 42–46.
Article CAS Google Scholar
Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ . (1988). Activating mutations for transformation by p53 produce a gene product that forms an hsc70–p53 complex with an altered half-life. Mol Cell Biol 8: 531–539.
Article CAS Google Scholar
Halevy O, Michalovitz D, Oren M . (1990). Different tumor-derived p53 mutants exhibit distinct biological activities. Science 250: 113–116.
Article CAS Google Scholar
Kim E, Deppert W . (2004). Transcriptional activities of mutant p53: when mutations are more than a loss. J Cell Biochem 93: 878–886.
Article CAS Google Scholar

Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Tumor Virology, Hamburg, Germany
W Deppert

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W Deppert
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Correspondence to W Deppert.

Deppert, W. Mutant p53: from guardian to fallen angel?. Oncogene 26, 2142–2144 (2007). https://doi.org/10.1038/sj.onc.1210276