Skip to main content

Advertisement

SpringerLink
Log in

Cross-talk between nuclear receptors and nuclear factor κB

  • Review
  • Published:
Oncogene Submit manuscript

Abstract

A variety of studies have shown that some activated nuclear receptors (NRs), especially the glucorticoid receptor, the estrogen receptor and peroxisome proliferator-activated receptor, can inhibit the activity of the transcription factor nuclear factor κB (NF-κB), which plays a key role in the control of genes involved in inflammation, cell proliferation and apoptosis. This review describes the molecular mechanisms of cross-talk between NRs and NF-κB and the biological relevance of this cross-talk. The importance and mechanistic aspects of selective NR modulation are discussed. Also included are future research prospects, which will lead to a new era in the field of NR research with the aim of specifically inhibiting NF-κB-driven gene expression for anti-inflammatory, anti-tumor and immune-modulatory purposes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2

Similar content being viewed by others

Abbreviations

AP-1:

activator protein-1

AR:

androgen receptor

Brg1:

brahma-related gene 1

BTM:

basal transcription machinery

CARM:

coactivator-associated arginine methyltransferase

COX:

cyclooxygenase

DBD:

DNA-binding domain

DRIP:

vitamin D receptor-interacting protein

ER:

estrogen receptor

FRAP:

fluorescence recovery after photobleaching

GILZ:

glucocorticoid-induced leucine zipper

GR:

glucocorticoid receptor

GRIP:

glucocorticoid receptor-interacting protein

(n)GRE:

(negative) glucocorticoid response element

HAT:

histone acetyltransferase

HDAC:

histone deacetylase

Hsp:

heat shock protein

IκB:

inhibitor κB

IKK:

IκB kinase

IL:

interleukin

iNOS:

inducible nitric oxide synthase

LBD:

ligand-binding domain

LSD1:

lysine-specific histone demethylase 1

LXR:

liver X receptor

MAPK:

mitogen-actived protein kinase

MKP-1:

mitogen-activated protein kinase phosphatase 1

MMP:

matrix metalloproteinase

MR:

mineralocorticoid receptor

MTA:

metastasis-associated protein

NcoR:

nuclear corepressor

NF-κB:

nuclear factor κB

NR:

nuclear receptor

PGC-1:

PPARγ coactivator-1

PPAR:

peroxisome proliferator-activated receptor

PK:

protein kinase

PLA:

phospholipase A

PR:

progesterone receptor

PSA:

prostate-specific antigen

p-TEFb:

transcription elongation factor

pol:

polymerase

RAR/RXR:

retinoid acid receptor/retinoid X receptor

SEGRM:

selective GR modulators

SERM:

selective ER modulators

SMRT:

silencing mediator of retinoic-acid and thyroid hormone receptors

SRC-1:

steroid receptor coactivator-1

TBL1:

transducin-β-like 1

TF:

transcription factor

TIF:

transcription intermediary factor

TLR:

toll-like receptor

TNF:

tumor necrosis factor

TR:

thyroid hormone receptor

TRAP:

thyroid receptor-activated protein

References

  • Aarnisalo P, Palvimo JJ, Jänne OA . (1998). Proc Natl Acad Sci USA 95: 2122–2127.

  • Adcock IM, Newton R, Barnes PJ . (1997). Biochem Soc Trans 25: 154s.

  • Ali S, Coombes C . (2002). Nat Rev Mol Cell Biol 2: 101–115.

  • Ammann P, Rizzoli R, Bonjour JP, Bourrin S, Meyer JM, Vassalli P et al. (1997). J Clin Invest 99: 1699–1703.

  • An J, Ribeiro RC, Webb P, Gustafsson JA, Kushner PJ, Baxter JD et al. (1999). Proc Natl Acad Sci USA 96: 15161–15166.

  • Auboeuf D, Dowhan DH, Dutertre M, Martin N, Berget SM, O'Malley BW . (2005). Mol Cell Biol 25: 5307–5316.

  • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M . (1995). Science 270: 286–290.

  • Baek SH, Rosenfeld MG . (2004). Biochem Biophys Res Commun 319: 707–714.

  • Barnes PJ . (2001). Allergy 56: 928–936.

  • Barnes PJ . (2006). Eur J Pharmacol 533: 2–14.

  • Bellentani S . (2005). Eur J Gastroenterol Hepatol 17: 137–140.

  • Bellido T, Jilka RL, Boyce BF, Girasole G, Broxmeyer H, Dalrymple SA et al. (1995). J Clin Invest 95: 2886–2895.

  • Belvisi MG, Brown TJ, Wicks S, Foster ML . (2001a). Pulm Pharmacol Ther 14: 221–227.

  • Belvisi MG, Wicks SL, Battram CH, Bottoms SE, Redford JE, Woodman P et al. (2001b). J Immunol 166: 1975–1982.

  • Bhat-Nakshatri P, Campbell RA, Patel NM, Newton TR, King AJ, Marshall MS et al. (2004). Br J Cancer 90: 853–859.

  • Bird A . (2003). Nat Immunol 4: 208–209.

  • Biswas DK, Shi Q, Baily S, Strickland I, Ghosh S, Pardee AB et al. (2004). Proc Natl Acad Sci USA 101: 10137–11042.

  • Biswas DK, Singh S, Shi Q, Pardee AB, Iglehart JD . (2005). Sci STKE 2005: pe27.

  • Björnström L, Sjöberg M . (2005). Mol Endocrinol 19: 833–842.

  • Borras C, Gambini J, Gomez-Cabrera MC, Sastre J, Pallardo FV, Mann GE et al. (2005). Aging Cell 4: 113–118.

  • Bosisio D, Marazzi I, Agresti A, Shimizu N, Bianchi M, Natoli G . (2006). EMBO J 25: 798–810.

  • Bowen NJ, Fujita N, Kajita M, Wade PA . (2004). Biochim Biophys Acta 1677: 52–57.

  • Buratowski S . (2003). Nat Struct Biol 10: 679–680.

  • Burkhart BA, Hebbar PB, Trotter KW, Archer TK . (2005). J Biol Chem 280: 6349–6358.

  • Cacquevel M, Lebeurrier N, Cheenne S, Vivien D . (2004). Curr Drug Targets 5: 529–534.

  • Caldenhoven E, Lidén J, Wissink S, Van de Stolpe A, Raaijmakers J, Koenderman L et al. (1995). Mol Endocrinol 9: 401–412.

  • Carlotti F, Dower SK, Qwarnstrom EE . (2000). J Biol Chem 275: 41028–41034.

  • Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P . (2003). J Biol Chem 278: 10443–10449.

  • Cato AC, Wade E . (1996). Bioessays 18: 371–378.

  • Cerillo G, Rees A, Manchanda N, Reilly C, Brogan I, White A et al. (1998). J Steroid Biochem Mol Biol 67: 79–88.

  • Chadwick CC, Chippari S, Matelan E, Borges-Marcucci L, Eckert AM, Keith Jr JC et al. (2005). Proc Natl Acad Sci USA 102: 2543–2548.

  • Chakalova L, Debrand E, Mitchell JA, Osborne CS, Fraser P . (2005). Nat Rev Genet 6: 669–677.

  • Chandran UR, DeFranco DB . (1999). Behav Brain Res 105: 29–36.

  • Chaudhary LR, Avioli LV . (1996). J Biol Chem 271: 16591–16596.

  • Chen J, Kinyamu HK, Archer TK . (2006). Mol Endocrinol 20: 1–13.

  • Cheung E, Schwabish MA, Kraus WL . (2003). EMBO J 22: 600–611.

  • Cinar B, De Benedetti A, Freeman MR . (2005). Cancer Res 65: 2547–2553.

  • Clark DE, Poteet-Smith CE, Smith JA, Lannigan DA . (2001). EMBO J 20: 3484–3494.

  • Coghlan MJ, Jacobson PB, Lane B, Nakane M, Lin CW, Elmore SW et al. (2003). Mol Endocrinol 17: 117–127.

  • Condon JC, Jeyasuria P, Faust JM, Wilson JW, Mendelson CR . (2003). Proc Natl Acad Sci USA 100: 9518–9523.

  • Condon JC, Hardy DB, Kovaric K, Mendelson CR . (2006). Mol Endocrinol 20: 764–775.

  • Cutolo M, Capellino S, Montagna P, Villaggio B, Sulli A, Seriolo B et al. (2003). Clin Exp Rheumatol 21: 687–690.

  • Cutolo M, Villaggio B, Seriolo B, Montagna P, Capellino S, Straub RH et al. (2004). Autoimmun Rev 3: 193–198.

  • Cvoro A, Tzagarakis-Foster C, Tatomer D, Paruthiyil S, Fox MS, Leitman DC . (2006). Mol Cell 21: 555–564.

  • Davie JR, Spencer VA . (1999). J Cell Biochem Suppl 32–33: 141–148.

  • De Bosscher K, Schmitz ML, Vanden Berghe W, Plaisance S, Fiers W, Haegeman G . (1997). Proc Natl Acad Sci USA 94: 13504–13509.

  • De Bosscher K, Vanden Berghe W, Beck IM, Van Molle W, Hennuyer N, Hapgood J et al. (2005). Proc Natl Acad Sci USA 102: 15827–15832.

  • De Bosscher K, Vanden Berghe W, Haegeman G . (2000a). J Neuroimmunol 109: 16–22.

  • De Bosscher K, Vanden Berghe W, Haegeman G . (2001). Mol Endocrinol 15: 219–227.

  • De Bosscher K, Vanden Berghe W, Haegeman G . (2003a) In: Beyaert R (ed). Nuclear Factor-kappaB: Regulation and Role in Diseases. Kluwer Academic Publishers: The Netherlands, pp 221–239.

    Book  Google Scholar 

  • De Bosscher K, Vanden Berghe W, Haegeman G . (2003b). Endocr Rev 24: 488–522.

  • De Bosscher K, Vanden Berghe W, Vermeulen L, Plaisance S, Boone E, Haegeman G . (2000b). Proc Natl Acad Sci USA 97: 3919–3924.

  • de Kloet E, Joels M, Holsboer F . (2005). Nat Rev Neurosci 6: 463–475.

  • DeFranco DB, Guerrero J . (2000). Crit Rev Eukaryot Gene Exp 10: 39–44.

  • Delany AM, Gabbitas BY, Canalis E . (1995). J Cell Biochem 57: 488–494.

  • Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ et al. (1999). J Biol Chem 274: 32048–32054.

  • Delerive P, De Bosscher K, Vanden Berghe W, Fruchart JC, Haegeman G, Staels B . (2002). Mol Endocrinol 16: 1029–1039.

  • Delerive P, Monte D, Dubois G, Trottein F, Fruchart-Najib J, Mariani J et al. (2001). EMBO Rep 2: 42–48.

  • Delfino FJ, Boustead JN, Fix C, Walker WH . (2003). Mol Cell Endocrinol 201: 1–12.

  • Dijsselbloem N, Vanden Berghe W, De Naeyer A, Haegeman G . (2004). Biochem Pharmacol 68: 1171–1185.

  • Doucas V, Shi Y, Miyamoto S, West A, Verma I, Evans RM . (2000). Proc Natl Acad Sci 97: 11893–11898.

  • Dutnall RN . (2003). Mol Cell 12: 3–4.

  • Dutta J, Fan Y, Gupta N, Fan G, Gélinas C . (2006). Oncogene this issue.

  • Egan KM, Lawson JA, Fries S, Koller B, Rader DJ, Smyth EM et al. (2004). Science 306: 1954–1957.

  • Eissenberg JC, Shilatifard A . (2006). Curr Opin Genet Dev 16: 184–190.

  • Espinosa L, Ingles-Esteve J, Robert-Moreno A, Bigas A . (2003). Mol Biol Cell 14: 491–502.

  • Eun CS, Han DS, Lee SH, Paik CH, Chung YW, Lee J et al. (2006). Dig Dis Sci 51: 693–697.

  • Forman BM, Chen J, Evans RM . (1996). Ann NY Acad Sci 804: 266–275.

  • Foster JS, Henley DC, Ahamed S, Wimalasena J . (2001a). Trends Endocrinol Metab 12: 320–327.

  • Foster JS, Henley DC, Bukovsky A, Seth P, Wimalasena J . (2001b). Mol Cell Biol 21: 794–810.

  • Francastel C, Schubeler D, Martin DI, Groudine M . (2000). Nat Rev Mol Cell Biol 1: 137–143.

  • Fujita N, Jaye DL, Kajita M, Geigerman C, Moreno CS, Wade PA . (2003). Cell 113: 207–219.

  • Fujita N, Kajita M, Taysavang P, Wade PA . (2004). Mol Endocrinol 18: 2937–2949.

  • Galien R, Garcia T . (1997). Nucleic Acids Res 25: 2424–2429.

  • Garside H, Stevens A, Farrow S, Normand C, Houle B, Berry A et al. (2004). J Biol Chem 279: 50050–50059.

  • Ghosh S, Karin M . (2002). Cell 109(Suppl): S81–S96.

  • Gilmore TD . (2006). Oncogene this issue.

  • Glass CK, Rosenfeld MG . (2000). Genes Dev 14: 121–141.

  • Glass CK, Ogawa S . (2006). Nat Rev Immunol 6: 44–55.

  • Glyn J . (1998). J Royal Soc Med 91: 513–517.

  • Gronemeyer H, Gustafsson JA, Laudet V . (2004). Nat Rev Drug Discov 3: 950–964.

  • Gururaj AE, Rayala SK, Vadlamudi RK, Kumar R . (2006). Clin Cancer Res 12: 1001s–11007s.

  • Haffner SM, Ruilope L, Dahlof B, Abadie E, Kupfer S, Zannad F . (2006). J Cardiovasc Pharmacol 47: 469–475.

  • Hager GL, Fletcher TM, Xiao N, Baumann CT, Muller WG, McNally JG . (2000). Biochem Soc Trans 28: 405–410.

  • Hall JM, McDonnell DP . (2005). Mol Interv 5: 343–357.

  • Hayden MS, Ghosh S . (2004). Genes Dev 18: 2195–2224.

  • Heck S, Kullmann M, Gast A, Ponta H, Rahmsdorf HJ, Herrlich P et al. (1994). EMBO J 13: 4087–4095.

  • Heldring N, Nilsson M, Buehrer B, Treuter E, Gustafsson JA . (2004). Mol Cell Biol 24: 3445–3459.

  • Helmberg A, Auphan N, Caelles C, Karin M . (1995). EMBO J 14: 452–460.

  • Hermoso MA, Matsuguchi T, Smoak K, Cidlowski JA . (2004). Mol Cell Biol 24: 4743–4756.

  • Hoberg JE, Popko AE, Ramsey CS, Mayo MW . (2006). Mol Cell Biol 26: 457–471.

  • Hofbauer LC, Khosla S . (1999). Eur J Endocrinol 140: 271–286.

  • Hoffmann A, Natoli G, Ghosh G . (2006). Oncogene? this issue.

  • Hofmann TG, Schmitz ML . (2002). Biol Chem 383: 1947–1951.

  • Irusen E, Matthews JG, Takahashi A, Barnes PJ, Chung KF, Adcock IM . (2002). J Allergy Clin Immunol 109: 649–657.

  • Ito K, Barnes PJ, Adcock IM . (2000). Mol Cell Biol 20: 6891–6903.

  • Ito K, Jazrawi E, Cosio B, Barnes PJ, Adcock IM . (2001). J Biol Chem 276: 30208–30215.

  • Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ et al. (2006). J Exp Med 203: 7–13.

  • Jehn BM, Osborne BA . (1997). Crit Rev Eukaryot Gene Exp 7: 179–193.

  • Johnson C, Van Antwerp D, Hope TJ . (1999). EMBO J 18: 6682–6693.

  • Jordan VC . (2002). Cancer Cell 1: 215–217.

  • Jordan VC . (2004). Cancer Cell 5: 207–213.

  • Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P . (2003). Nat Med 9: 213–219.

  • Joseph SB, Tontonoz P . (2003). Curr Opin Pharmacol 3: 192–197.

  • Kalaitzidis D, Gilmore TD . (2005). Trends Endocrinol Metab 16: 46–52.

  • Kalkhoven E, Wissink S, van der Saag PT, van der Burg B . (1996). J Biol Chem 271: 6217–6224.

  • Kao HY, Verdel A, Tsai CC, Simon C, Juguilon H, Khochbin S . (2001). J Biol Chem 276: 47496–47507.

  • Kassel O, Sancono A, Krätzschmar J, Kreft B, Stassen M, Cato CB . (2001). EMBO J 20: 7108–7116.

  • Katzenellenbogen BS, Katzenellenbogen JA . (2002). Science 295: 2380–2381.

  • Kelly D, Campbell JI, King TP, Grant G, Jansson EA, Coutts AG et al. (2004). Nat Immunol 5: 104–112.

  • Kian Tee M, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ et al. (2004). Mol Biol Cell 15: 1262–1272.

  • Kim MY, Woo EM, Chong YT, Homenko DR, Kraus WL . (2006). Mol Endocrinol 20: 1479–1493.

  • Kirillov A, Kistler B, Mostoslavsky R, Cedar H, Wirth T, Bergman Y . (1996). Nat Genet 13: 435–441.

  • Kliewer SA, Willson TM . (1998). Curr Opin Genet Dev 8: 576–581.

  • Koehn FE, Carter GT . (2005). Nat Rev Drug Discov 4: 206–220.

  • Kong EH, Heldring N, Gustafsson JA, Treuter E, Hubbard RE, Pike AC . (2005). Proc Natl Acad Sci USA 102: 3593–3598.

  • Kwon HJ, Breese EH, Vig-Varga E, Luo Y, Lee Y, Goebl MG et al. (2004). Mol Cell Biol 24: 9317–9326.

  • Lanz RB, Chua SS, Barron N, Soder BM, DeMayo F, O'Malley BW . (2003). Mol Cell Biol 23: 7163–7176.

  • Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY et al. (1999). Cell 97: 17–27.

  • Lanz RB, Razani B, Goldberg AD, O'Malley BW . (2002). Proc Natl Acad Sci USA 99: 16081–16086.

  • Lasa M, Abraham SM, Boucheron C, Saklatvala J, Clark AR . (2002). Mol Cell Biol 22: 7802–7811.

  • Lasa M, Brook M, Saklatvala J, Clark RA . (2001). Mol Cell Biol 21: 771–780.

  • Leclercq G, Lacroix M, Laios I, Laurent G . (2006). Curr Cancer Drug Targets 6: 39–64.

  • Lee DY, Northrop JP, Kuo MH, Stallcup MR . (2006). J Biol Chem 281: 8476–8485.

  • Lee SK, Kim JH, Lee YC, Cheong J, Lee JW . (2000). J Biol Chem 275: 12470–12474.

  • Lemon B, Tjian T . (2000). Genes Dev 14: 2551–2569.

  • Leung TH, Hoffmann A, Baltimore D . (2004). Cell 118: 453–464.

  • Lewis BA, Reinberg D . (2003). J Cell Sci 116: 3667–3675.

  • Li AC, Binder CJ, Gutierrez A, Brown KK, Plotkin CR, Pattison JW et al. (2004). J Clin Invest 114: 1564–1576.

  • Li J, Lin Q, Yoon HG, Huang ZQ, Strahl BD, Allis CD et al. (2002). Mol Cell Biol 22: 5688–5697.

  • Lidén J, Delaunay F, Rafter I, Gustafsson J, Okret S . (1997). J Biol Chem 272: 21467–21472.

  • Lidén J, Rafter I, Truss M, Gustafsson JA, Okret S . (2000). Biochem Biophys Res Commun 273: 1008–1014.

  • Liu J, DeFranco DB . (1999). Mol Endocrinol 13: 355–365.

  • Lösel R, Wehling M . (2003). Nat Rev Mol Cell Biol 4: 46–56.

  • Lu T, Sathe SS, Swiatkowski SM, Hampole CV, Stark GR . (2004). Oncogene 23: 2138–2145.

  • Luecke HF, Yamamoto KR . (2005). Genes Dev 19: 1116–1127.

  • Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U . (2004). Science 303: 95–98.

  • Malik S, Roeder RG . (2000). Trends Biochem Sci 25: 277–283.

  • Manavathi B, Kumar R . (2006). J Cell Physiol 207: 594–604.

  • Maret A, Clamens S, Delrieu I, Elhage R, Arnal JF, Bayard F . (1999). Endocrinology 140: 2876–2882.

  • Markham A, Bryson HM . (1995). Drugs 50: 317–333.

  • Martens C, Bilodeau S, Maira M, Gauthier Y, Drouin J . (2005). Mol Endocrinol 19: 885–897.

  • McDonnell DP, Norris JD . (2002). Science 296: 1642–1644.

  • McKay LI, Cidlowski JA . (2000). Mol Endocrinol 14: 1222–1234.

  • McKenna NJ, O'Malley BW . (2002). Endocrinology 143: 2461–2465.

  • Meaney MJ, Szyf M . (2005). Dialogues Clin Neurosci 7: 103–123.

  • Mendelson CR, Condon JC . (2005). J Steroid Biochem Mol Biol 93: 113–119.

  • Métivier R, Penot G, Hubner MR, Reid G, Brand H, Kos M et al. (2003). Cell 115: 751–763.

  • Métivier R, Reid G, Gannon F . (2006). EMBO Rep 7: 161–167.

  • Metzger E, Wissmann M, Yin N, Muller JM, Schneider R, Peters AH et al. (2005). Nature 437: 436–439.

  • Meyer T, Carlstedt Duke J, Starr DB . (1997). J Biol Chem 272: 30709–30714.

  • Miao F, Li S, Chavez V, Lanting L, Natarajan R . (2006). Mol Endocrinol 20: 1562–1573.

  • Miner JN . (2002). Biochem Pharmacol 64: 355–361.

  • Miska EA, Langley E, Wolf D, Karlsson C, Pines J, Kouzarides T . (2001). Nucleic Acids Res 29: 3439–3447.

  • Miura T, Ouchida R, Yoshikawa N, Okamoto K, Makino Y, Nakamura T et al. (2001). J Biol Chem 276: 47371–47378.

  • Moras D, Gronemeyer H . (1998). Curr Opin Cell Biol 10: 384–391.

  • Murayama A, Sakura K, Nakama M, Yasuzawa-Tanaka K, Fujita E, Tateishi Y et al. (2006). EMBO J 25: 1081–1092.

  • Nakajima Y, DelliPizzi AM, Mallouh C, Ferreri NR . (1996). Prostate 29: 296–302.

  • Natoli G, Saccani S, Bosisio D, Marazzi I . (2005). Nat Immunol 6: 439–445.

  • Natoli G, De Santa F . (2006). Cell Death Differ 13: 693–696.

  • Necela BM, Cidlowski JA . (2003). Trends Pharmacol Sci 24: 58–61.

  • Nelson HC . (1995). CurrOpin Genet Dev 5: 180–189.

  • Neve BP, Fruchart JC, Staels B . (2000). Biochem Pharmacol 60: 1245–1250.

  • Nilsson S, Makela S, Treuter E, Tujague M, Thomsen J, Andersson G et al. (2001). Physiol Rev 81: 1535–1565.

  • Nissen RM, Yamamoto KR . (2000). Genes Dev 14: 2314–2329.

  • Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS . (2002). Mol Cell Biol 22: 3437–3449.

  • Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R et al. (2004). Proc Natl Acad Sci USA 101: 14461–14466.

  • Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S et al. (2005). Cell 122: 707–721.

  • Olivier S, Close P, Castermans E, de Leval L, Tabruyn S, Chariot A et al. (2006). Mol Pharmacol 69: 1615–1623.

  • Pacifici R . (1996). J Bone Miner Res 11: 1043–1051.

  • Pahl HL . (1999). Oncogene 18: 6853–6866.

  • Palvimo JJ, Reinikainen P, Ikonen T, Kallio PJ, Moilanen A, Jänne OA . (1996). J Biol Chem 271: 24151–24156.

  • Panta GR, Kaur S, Cavin LG, Cortes ML, Mercurio F, Lothstein L et al. (2004). Mol Cell Biol 24: 1823–1835.

  • Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V et al. (2005). Nature 437: 759–763.

  • Paumelle R, Blanquart C, Briand O, Barbier O, Duhem C, Woerly G et al. (2006). Circ Res 98: 361–369.

  • Pearce ST, Liu H, Jordan VC . (2003). J Biol Chem 278: 7630–7638.

  • Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG . (2004). Cell 116: 511–526.

  • Perissi V, Rosenfeld MG . (2005). Nat Rev Mol Cell Biol 6: 542–554.

  • Perkins ND . (2006). Oncogene this issue.

  • Peters AH, Kubicek S, Mechtler K, O'Sullivan RJ, Derijck AA, Perez-Burgos L et al. (2003). Mol Cell 12: 1577–1589.

  • Phillips A, Maira M, Mullick A, Chamberland M, Lesage S, Hugo P et al. (1997). Mol Cell Biol 17: 5952–5959.

  • Pratt MA, Bishop TE, White D, Yasvinski G, Menard M, Niu MY et al. (2003). Mol Cell Biol 23: 6887–6900.

  • Pratt WB, Toft DO . (1997). Endocr Rev 18: 306–360.

  • Ramirez-Carrozzi V, Nazarian A, Sarah C, Gore L, Sridharan R, Imbalzano A et al. (2006). Genes Dev 20: 282–296.

  • Ray A, Prefontaine KE . (1994). Proc Natl Acad Sci USA 91: 752–756.

  • Ray A, Prefontaine KE, Ray P . (1994). J Biol Chem 269: 12940–12946.

  • Ray A, Zhang DH, Siegel MD, Ray P . (1995). Ann NY Acad Sci 762: 79–87.

  • Reichardt HM, Kaestner KH, Tuckermann J, Kretz O, Wessely O, Bock R et al. (1998). Cell 93: 531–541.

  • Reichardt HM, Tronche F, Berger S, Kellendonk C, Schütz G . (2000). Adv Pharmacol 47: 1–21.

  • Reichardt HM, Tuckermann JP, Gottlicher M, Vujic M, Weih F, Angel P et al. (2001). EMBO J 20: 7168–7173.

  • Reily MM, Pantoja C, Hu X, Chinenov Y, Rogatsky I . (2006). EMBO J 25: 108–117.

  • Resche-Rigon M, Gronemeyer H . (1998). Curr Opin Chem Biol 2: 501–507.

  • Robinson-Rechavi M, Escriva Garcia H, Laudet V . (2003). J Cell Sci 116: 585–586.

  • Rogatsky I, Logan SK, Garabedian MJ . (1998). Proc Natl Acad Sci USA 95: 2050–2055.

  • Rogatsky I, Luecke HF, Leitman DC, Yamamoto KR . (2002). Proc Natl Acad Sci USA 99: 16701–16706.

  • Rosenfeld MG, Lunyak VV, Glass CK . (2006). Genes Dev 20: 1405–1428.

  • Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M et al. (2000). Nature 403: 103–108.

  • Roux S, Terouanne B, Couette B, Rafestin-Oblin ME, Nicolas JC . (1999). J Biol Chem 274: 10059–10065.

  • Salojin KV, Owusu IB, Millerchip KA, Potter M, Platt KA, Oravecz T . (2006). J Immunol 176: 1899–1907.

  • Sapolsky RM, Romero LM, Munck AU . (2000). Endocr Rev 21: 55–89.

  • Savory JG, Hsu B, Laquian IR, Giffin W, Reich T, Hache RJ et al. (1999). Mol Cell Biol 19: 1025–1037.

  • Scheinman R, Cogswell PC, Lofquist A, Baldwin AS . (1995). Science 270: 283–286.

  • Scheidereit C . (2006). Oncogene this issue.

  • Schotta G, Lachner M, Peters AH, Jenuwein T . (2004). Novartis Found Symp 259: 22–37.

  • Schulz M, Eggert M, Baniahmad A, Dostert A, Heinzel T, Renkawitz R . (2002). J Biol Chem 277: 26238–26243.

  • Shang Y, Brown M . (2002). Science 295: 2465–2468.

  • Sheppard K-A, Phelps KM, Williams AJ, Thanos D, Glass CK, Rosenfeld MG et al. (1998). J Biol Chem 273: 29291–29294.

  • Shilatifard A . (2006). Annu Rev Biochem 75: 243–269.

  • Shuto T, Imasato A, Jono H, Sakai A, Xu H, Watanabe T et al. (2002). J Biol Chem 277: 17263–17270.

  • Smoak KA, Cidlowski JA . (2004). Mech Ageing Dev 125: 697–706.

  • Sowers JR . (2003). Am J Cardiol 91: 14B–22B.

  • Spiegelman BM, Heinrich R . (2004). Cell 119: 157–167.

  • Staels B, Koenig W, Habib A, Merval R, Lebret M, Torra IP et al. (1998). Nature 393: 790–793.

  • Stavreva DA, Muller WG, Hager GL, Smith CL, McNally JG . (2004). Mol Cell Biol 24: 2682–2697.

  • Stein B, Yang MX . (1995). Mol Cell Biol 15: 4971–4979.

  • Stenoien DL, Mancini MG, Patel K, Allegretto EA, Smith CL, Mancini MA . (2000). Mol Endocrinol 15: 518–534.

  • Stewart S, Crabtree GR . (2000). Nature 408: 46–47.

  • Straus DS, Pascual G, Li M, Welch JS, Ricote M, Hsiang CH et al. (2000). Proc Natl Acad Sci USA 97: 4844–4849.

  • Suh J, Payvandi F, Edelstein LC, Amenta PS, Zong WX, Gélinas C et al. (2002). Prostate 52: 183–200.

  • Suh J, Rabson AB . (2004). J Cell Biochem 91: 100–117.

  • Supakar PC, Jung MH, Song CS, Chatterjee B, Roy AK . (1995). J Biol Chem 270: 837–842.

  • Szyf M, Weaver IC, Champagne FA, Diorio J, Meaney MJ . (2005). Front Neuroendocrinol 26: 139–162.

  • Thomassin H, Flavin M, Espinas ML, Grange T . (2001). EMBO J 20: 1974–1983.

  • Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, Fey MF . (1992). Blood 79: 45–51.

  • Torchia J, Glass C, Rosenfeld MG . (1998). Curr Opin Cell Biol 10: 373–383.

  • Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G . (1999a). J Biol Chem 274: 32091–32098.

  • Vanden Berghe W, Francesconi E, De Bosscher K, Rèsche-Rigon M, Haegeman G . (1999b). Mol Pharmacol 56: 797–806.

  • Vanden Berghe W, Dijsselbloem N, Vermeulen L, Ndlovu M, Boone E, Haegeman G . (2006a). Cancer Res 66: 4852–4862.

  • Vanden Berghe W, Ndlovu M, Hoya-Arias R, Dijsselbloem N, Gerlo S, Haegeman G . (2006b). Biochem Pharmacol. doi:10.1016/j.bq.2006.07.012.

  • Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W et al. (1998). J Biol Chem 273: 3285–3290.

  • Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar-Sinha C, Sanda MG et al. (2002). Nature 419: 624–629.

  • Vayssière BM, Dupont S, Choquart A, Petit F, Garcia T, Marchandeau C et al. (1997). Mol Endocrinol 11: 1245–1255.

  • Vermeulen L, De Wilde G, Van Damme P, Vanden Berghe W, Haegeman G . (2003). EMBO J 22: 1313–1324.

  • Vina J, Borras C, Gambini J, Sastre J, Pallardo FV . (2005). FEBS Lett 579: 2541–2545.

  • Wang Q, Carroll JS, Brown M . (2005). Mol Cell 19: 631–642.

  • Wang JC, Shah N, Pantoja C, Meijsing SH, Ho JD, Scanlan TS et al. (2006). Genes Dev 20: 689–699.

  • Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR et al. (2004). Nat Neurosci 7: 847–854.

  • West AG, Fraser P . (2005). Hum Mol Genet 14: R101–R111.

  • Widén C, Gustafsson JA, Wikstrom AC . (2003). Biochem J 373: 211–220.

  • Wissink S, van Heerde EC, Schmitz ML, Kalkhoven E, van der Burg B, Baeuerle PA et al. (1997). J Biol Chem 272: 22278–22284.

  • Wissink S, van der Burg B, Katzenellenbogen BS, van der Saag PT . (2001). Mol Endocrinol 15: 543–552.

  • Wu H, Chen Y, Liang J, Shi B, Wu G, Zhang Y et al. (2005a). Nature 438: 981–987.

  • Wu J, Li Y, Dietz J, Lala DS . (2004). Mol Endocrinol 18: 53–62.

  • Wu RC, Smith CL, O'Malley BW . (2005b). Endocr Rev 26: 393–399.

  • Wu YL, Yang X, Ren Z, McDonnell DP, Norris JD, Willson TM et al. (2005c). Mol Cell 18: 413–424.

  • Xu W, Cho H, Evans RM . (2003). Methods Enzymol 364: 205–223.

  • Xu W, Cho H, Kadam S, Banayo EM, Anderson S, Yates III JR et al. (2004). Genes Dev 18: 144–156.

  • Yamada T, Yamaguchi Y, Inukai N, Okamoto S, Mura T, Handa H . (2006). Mol Cell 21: 227–237.

  • Yamamoto Y, Gaynor RB . (2004). Trends Biochem Sci 29: 72–79.

  • Zhong H, Voll RE, Ghosh S . (1998). Mol Cell 1: 661–671.

  • Zhou Y, Eppenberger-Castori S, Eppenberger U, Benz CC . (2005a). Endocr Relat Cancer 12: S37–S46.

  • Zhou Y, Eppenberger-Castori S, Marx C, Yau C, Scott GK, Eppenberger U et al. (2005b). Int J Biochem Cell Biol 37: 1130–1144.

Download references

Acknowledgements

We thank the University of Gent, the IAP and Marató programs, and the FWO-Vlaanderen for financial support. KDB and WVB are postdoctoral fellows with the FWO-Vlaanderen.

Author information

Authors and Affiliations

  1. Department of Molecular Biology, Laboratory for Eukaryotic Gene Expression and Signal Transduction (LEGEST), Ghent University, Gent, Belgium

    K De Bosscher, W Vanden Berghe & G Haegeman

Authors
  1. K De Bosscher
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W Vanden Berghe
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G Haegeman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to K De Bosscher.

Rights and permissions

Reprints and permissions

About this article

Cite this article

De Bosscher, K., Vanden Berghe, W. & Haegeman, G. Cross-talk between nuclear receptors and nuclear factor κB. Oncogene 25, 6868–6886 (2006). https://doi.org/10.1038/sj.onc.1209935

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.onc.1209935

  • Springer Nature Limited

Keywords

This article is cited by

Search

Navigation