Skip to main content
SpringerLink
Log in

Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit/hyperactivity disorder

  • Letter to the Editor
  • Published:
Molecular Psychiatry Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Arnsten AF, Steere JC, Hunt RD . The contribution of alpha-2-noradrenergic mechanisms to prefrontal cortical cognitive function: potential significance for attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 1996; 53: 448–455.

    Article  CAS  Google Scholar 

  2. Biederman J, Spencer T . Attention-deficit/hyperactivity disorder (ADHD) as a noradrenergic disorder. Biol Psychiatry 1999; 46: 1234–1242.

    Article  CAS  Google Scholar 

  3. Comings DE, Gade-Andavolu R, Gonzalez N, Blake H, Wu S, Mac-Murray JP . Additive effect of three noradrenergic genes (ADRA2A, ADRA2C, DBH) on attention-deficit/hyperactivity disorder and learning disabilities in Tourette syndrome subjects. Clin Genet 1999; 55: 160–172.

    Article  CAS  Google Scholar 

  4. Xu C, Schachar R, Tannock R, Roberts W, Malone M, Kennedy JL et al. Linkage study of the α2A-adrenergic receptor in attention-deficit/hyperactivity disorder. Am J Med Genet (Neuropsychiatr Genet) 2001; 105: 159–162.

    Article  CAS  Google Scholar 

  5. Roman T, Schmitz M, Polanczyk G, Eizirik M, Rohde LA, Hutz M . Is the α-2a adrenergic receptor gene (ADRA2A) associated with attention-deficit/hyperactivity disorder? Am J Med Genet (Neuropsychiatr Genet) 2003; 120B: 116–120.

    Article  Google Scholar 

  6. Park L, Nigg JT, Waldman ID, Nummy KA, Huang-Pollock C, Rappley M et al. Association and linkage of alpha-2A-adrenergic receptor gene polymorphisms with childhood ADHD. Mol Psychiatry 2005; 10: 572–580.

    Article  CAS  Google Scholar 

  7. Polanczyk G, Zeni C, Genro JP, Roman T, Hutz MH, Rohde LA . Attention-deficit/hyperactivity disorder: advancing on pharmacogenomics. Pharmacogenomics 2005; 6: 225–234.

    Article  CAS  Google Scholar 

  8. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th Edition. Washington, DC: American Psychiatric Association, 1994.

  9. Swanson JM, Kraemer HC, Hinshaw SP, Arnold LE, Conners CK, Abikoff HB et al. Clinical relevance of the primary findings of the MTA: success rates based on severity of ADHD and ODD symptoms at the end of treatment. J Am Acad Child Adolesc Psychiatry 2001; 40: 168–179.

    Article  CAS  Google Scholar 

  10. Talmud PJ, Humphries SE . Genetic polymorphisms, lipoproteins and coronary artery disease risk. Curr Opin Lipidol 2001; 12: 405–409.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Morphological Sciences, Federal School of Medical Sciences of Porto Alegre, Porto Alegre, RS, Brazil

    T Roman

  2. Department of Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil

    G V Polanczyk, C Zeni & L A Rohde

  3. Department of Genetics, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil

    J P Genro & M H Hutz

Authors
  1. T Roman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G V Polanczyk
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C Zeni
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J P Genro
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. L A Rohde
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. M H Hutz
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Roman, T., Polanczyk, G., Zeni, C. et al. Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit/hyperactivity disorder. Mol Psychiatry 11, 8–10 (2006). https://doi.org/10.1038/sj.mp.4001743

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.mp.4001743

  • Springer Nature Limited

This article is cited by

Search

Navigation