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Knocking out the stress response

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Abstract

Transgenic animals and knockout mice have been generated with defined defects in various components of the hypothalamic-pituitary-adrenal axis and the autonomic nervous system. These models provide valuable and novel insights into the development, crosstalk, organization, and functioning of the stress system.

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Authors and Affiliations

  1. Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, 20892, MD, USA

    S R Bornstein & G P Chrousos

  2. Department of Internal Medicine, University of Leipzig, Leipzig, 04103, Germany

    A Böttner

Authors
  1. S R Bornstein
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  2. A Böttner
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  3. G P Chrousos
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Correspondence to S R Bornstein.

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Bornstein, S., Böttner, A. & Chrousos, G. Knocking out the stress response. Mol Psychiatry 4, 403–407 (1999). https://doi.org/10.1038/sj.mp.4000602

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  • DOI: https://doi.org/10.1038/sj.mp.4000602

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