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Aβ peptide deposition in the brains of transgenic mice: evidence for a key event in Alzheimer's disease pathogenesis

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Abstract

Transgenic technology has led to the generation of several animal models for Alzheimer's disease. These transgenic mice surprisingly reproduce many aspects of the pathological alterations observed in Alzheimer's disease patients.

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Authors and Affiliations

  1. Nervous System Research, Novartis Pharma Inc, Basel, CH-4002, Switzerland

    B Sommer & M Staufenbiel

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  1. B Sommer
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  2. M Staufenbiel
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Sommer, B., Staufenbiel, M. Aβ peptide deposition in the brains of transgenic mice: evidence for a key event in Alzheimer's disease pathogenesis. Mol Psychiatry 3, 284–286 (1998). https://doi.org/10.1038/sj.mp.4000397

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  • DOI: https://doi.org/10.1038/sj.mp.4000397

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