Abstract
This issue features an article by Lynch, Shivers and colleagues (pages 227–238) which presents a novel, cell-permeable cysteine protease inhibitor, boc-aspartyl(OMe)-fluoromethylketone (boc-Asp-CH2F, abbreviated BAF). This inhibitor is an important new tool available to the research community and may represent a harbinger of a new class of chemicals useful in the treatment of human disease. In order to understand the value of BAF, we need to take a step back and examine the current concepts on the role of apoptosis in human disease.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wolozin, B. ICE and apoptosis. Mol Psychiatry 2, 184–187 (1997). https://doi.org/10.1038/sj.mp.4000243
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/sj.mp.4000243
- Springer Nature Limited