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Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome

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References

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Acknowledgements

We thank the Leukaemia Research Fund for financial support; Dr Anne Hagermeijer (EU Concerted Action) and Dr Roland Berger (Paris) for cosmids ICRF c103C0664 and H11086, respectively; Dr John Crolla and his team, Wessex Regional Genetics Laboratory, Salisbury, for growing and preparation of the AML1-specific cosmids; the Clinical Trial Service Unit (CTSU), Oxford, for clinical and survival data. We are grateful to the following UKCCG cytogenetic laboratories for providing cytogenetic and FISH data as well as fixed cell suspensions: West Midlands Regional Genetics Services, Birmingham Women's Hospital; Haematology Cytogenetics Laboratory, University Hospital of Wales, Cardiff; SE Scotland Cytogenetics Services, Western General Hospital, Edinburgh; LRF Centre for Childhood Leukemia, Great Ormond Street Hospital, London; Cytogenetics Department, St James Hospital, Leeds; Merseyside & Cheshire Genetics Laboratory, Liverpool Women's Hospital, Liverpool; Oncology Cytogenetics Service, Christie Hospital, Manchester; North Trent Cytogenetics Service, Sheffield Children's Hospital NHS Trust, Sheffield.

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Authors and Affiliations

  1. Cancer Sciences Division, Leukaemia Research Fund Cytogenetics Group, University of Southampton, Southampton, UK

    H M Robinson, Z J Broadfield, K L Cheung, L Harewood, R L Harris, G R Jalali, M Martineau, A V Moorman, K E Taylor & C J Harrison

  2. Clinical Trial Service Unit, Radcliffe Infirmary, Oxford, UK

    S Richards

  3. Paediatric Oncology, John Radcliffe Hospital, Oxford, UK

    C Mitchell

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  1. H M Robinson
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  2. Z J Broadfield
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  3. K L Cheung
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  4. L Harewood
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  5. R L Harris
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  6. G R Jalali
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  7. M Martineau
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  9. K E Taylor
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  10. S Richards
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  11. C Mitchell
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  12. C J Harrison
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Robinson, H., Broadfield, Z., Cheung, K. et al. Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome. Leukemia 17, 2249–2250 (2003). https://doi.org/10.1038/sj.leu.2403140

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  • DOI: https://doi.org/10.1038/sj.leu.2403140

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