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MLL partial tandem duplications in acute leukemia cell lines

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References

  1. Ernst P, Wang J, Korsmeyer SJ . The role of MLL in hematopoiesis and leukemia.Curr Opin Hematol 2002; 9: 282–287.

    Article  PubMed  Google Scholar 

  2. Schnittger S, Kinkelin U, Schoch C, Heinecke A, Haase D, Haferlach T et al. Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML. Leukemia 2000; 14: 796–804.

    Article  CAS  PubMed  Google Scholar 

  3. Yamamoto K, Seto M, Iida S, Komatsu H, Kamada N, Kojima S et al. A reverse transcriptase-polymerase chain reaction detects heterogeneous chimeric mRNAs in leukemias with 11q23 abnormalities. Blood 1994; 83: 2912–2921.

    CAS  PubMed  Google Scholar 

  4. Tanabe S, Zeleznik-Le NJ, Kobayashi H, Vignong C, Espinosa R, LeBeau MM et al. Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line. Genes Chromosomes Cancer 1996; 15: 206–216.

    Article  CAS  PubMed  Google Scholar 

  5. Kakuda H, Sato T, Hayashi Y, Enomoto Y, Takayama J, Ohira M et al. A novel human leukaemic cell line, CTS, has a t(6;11) chromosomal translocation and characteristics of pluripotent stem cells. Br J Haematol 1996; 95: 306–318.

    Article  CAS  PubMed  Google Scholar 

  6. Ikeda T, Sasaki K, Ikeda K, Yamaoka G, Kawanishi K, Kawachi Y et al. A new cytokine-dependent monoblastic cell line with t(9;11)(p22;q23) differentiates to macrophages with macrophage colony-stimulating factor (M-CSF) and to osteoclast-like cells with M-CSF and interleukin-4. Blood 1998; 91: 4543–4553.

    CAS  PubMed  Google Scholar 

  7. Quentmeier H, Reinhardt J, Zaborski M, Drexler H . FLT3 mutations in acute myeloid leukemia cell lines. Leukemia 2003; 17: 120–124.

    Article  CAS  PubMed  Google Scholar 

  8. Jamal R, Taketani T, Taki T, Bessho F, Hongo T, Hamaguchi H et al. Coduplication of the MLL and FLT3 genes in patients with acute myeloid leukemia. Genes Chromosomes Cancer 2001; 31: 187–190.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

We thank Dr Susanne Schnittger (University of Munich, Germany) for providing MLL PTD cDNA as positive control.

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Authors and Affiliations

  1. Department of Human and Animal Cell Cultures, DSMZ – German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany

    H Quentmeier, J Reinhardt, M Zaborski & H G Drexler

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  1. H Quentmeier
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  2. J Reinhardt
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  3. M Zaborski
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  4. H G Drexler
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Quentmeier, H., Reinhardt, J., Zaborski, M. et al. MLL partial tandem duplications in acute leukemia cell lines. Leukemia 17, 980–981 (2003). https://doi.org/10.1038/sj.leu.2402911

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