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Abnormalities of the p16INK4a gene in childhood B-precursor acute lymphoblastic leukemia without nonrandom translocations: analysis of seven matched pairs of primary leukemia and corresponding cell line

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References

  1. Quesnel B, Preudhomme C, Philippe N, Vanrumbeke M, Dervite I, Lai JL, Bauters F, Wattel E, Fenaux P . p16 gene homozygous deletions in acute lymphoblastic leukemia Blood 1995 85: 657–663

    CAS  PubMed  Google Scholar 

  2. Ogawa S, Hangaishi A, Miyawaki S, Hirosawa S, Miura Y, Takeyama K, Kamada N, Ohtake S, Uike N, Shimazaki C, Toyama K, Hirano M, Mizoguchi H, Kobayashi Y, Furusawa S, Saito M, Emi N, Yazaki Y, Ueda R, Hirai H . Loss of the cyclin-dependent kinase 4-inhibitor (p16; MTS1) gene is frequent and highly specific to lymphoid tumors in primary human hematopoietic malignancies Blood 1995 86: 1548–1556

    CAS  PubMed  Google Scholar 

  3. Siebert R, Willers CP, Schramm A, Fossa A, Gana Dresen IM, Uppenkamp M, Nowrousian MR, Seeber S, Opalka B . Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukemia cell lines Br J Haematol 1995 91: 350–354

    Article  CAS  Google Scholar 

  4. Kees UR, Ranford PR, Hatzis M . Deletions of the p16 gene in pediatric leukemia and corresponding cell lines Oncogene 1996 12: 2235–2239

    CAS  PubMed  Google Scholar 

  5. Maloney KW, McGavran L, Odom LF, Hunger SP . Acquisition of p16INK4A and p15INK4B gene abnormalities between initial diagnosis and relapse in children with acute lymphoblastic leukemia Blood 1999 93: 2380–2385

    CAS  PubMed  Google Scholar 

  6. Nakamura M, Sugita K, Inukai T, Goi K, Iijima K, Tezuka T, Kojika S, Shiraishi K, Miyamato N, Karakida N, Kagami K, O-Koyama T, Mori T, Nakazawa S . p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in childhood acute lymphoblastic leukemia with 11q23 translocation Leukemia 1999 13: 884–890

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, Yamanashi, Medical University, Yamanashi, Japan

    M Nakamura, K Sugita, T Inukai, K Goi, N Miyamoto, K Kagami, M Saito & S Nakazawa

  2. Department of Pediatrics, Saitama, Shakaihoken Hospital, Saitama, Japan

    T Okazaki-Koyama & T Mori

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  1. M Nakamura
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  2. K Sugita
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  3. T Inukai
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  4. K Goi
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  5. N Miyamoto
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  6. K Kagami
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  7. T Okazaki-Koyama
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  8. T Mori
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  9. M Saito
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  10. S Nakazawa
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Nakamura, M., Sugita, K., Inukai, T. et al. Abnormalities of the p16INK4a gene in childhood B-precursor acute lymphoblastic leukemia without nonrandom translocations: analysis of seven matched pairs of primary leukemia and corresponding cell line. Leukemia 15, 1136–1139 (2001). https://doi.org/10.1038/sj.leu.2402160

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  • DOI: https://doi.org/10.1038/sj.leu.2402160

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