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Lack of p73 expression in mature B-ALL and identification of three new splicing variants restricted to pre B and C-ALL indicate a role of p73 in B cell ALL differentiation

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  1. Kaghad M, Bonnet H, Yang A, Creancier L, Biscan J, Valent A, Minty A, Chalon P, Lelias J, Dumont X, Ferrara P, McKeon F, Caput D . Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers Cell 1997 90: 809–819

    Article  CAS  Google Scholar 

  2. De Laurenzi V, Catani MV, Terrinoni A, Corazzari M, Melino G, Costanzo A, Levrero M, Knight RA . Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ Cell Death Diff 1999 6: 389–390

    Article  CAS  Google Scholar 

  3. Kawano S, Miller CW, Gombart AF, Bartram CR, Matsuo Y, Sakashita A, Said J, Tatsumi E, Koeffler HP . Loss of p73 gene expression in leukemia/lymphomas due to hypermethylation Blood 1999 94: 1113–1120

    CAS  PubMed  Google Scholar 

  4. Corn PG, Kuerbitz SJ, van Noesel MM, Esteller M, Compitello N, Baylin SB, Herman JG . Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5I CpG island methylation Cancer Res 1999 59: 3352–3356

    CAS  PubMed  Google Scholar 

  5. Casciano I, Ponzoni M, Lo Cunsolo C, Tonini GP, Romani M . Different p73 splicing variants are expressed in distinct tumour areas of a multifocal neuroblastoma Cell Death Diff 1999 6: 391–393

    Article  CAS  Google Scholar 

  6. Romani M, Scaruffi P, Casciano I, Mazzocco K, Lo Cunsolo C, Cavazzana A, Gambini C, Boni L, De Bernardi B, Tonini GP . Stage-independent expression and genetic analysis of TP73 in neuroblastoma Int J Cancer 1999 84: 365–369

    Article  CAS  Google Scholar 

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Acknowledgements

This work was partially supported by Associazione Italiana per la Ricerca sul Cancro (AIRC), Associazione Italiana per la Lotta al Neuroblastoma, Associazione Città della Speranza. PS is supported by a FIRC (Fondazione Italiana Ricerca sul Cancro) fellowship.

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Scaruffi, P., Casciano, I., Masiero, L. et al. Lack of p73 expression in mature B-ALL and identification of three new splicing variants restricted to pre B and C-ALL indicate a role of p73 in B cell ALL differentiation. Leukemia 14, 518–519 (2000). https://doi.org/10.1038/sj.leu.2401698

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