Skip to main content

Advertisement

SpringerLink
Log in

A case of acute eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression and response to all-trans retinoic acid

  • Correspondence
  • Published:
Leukemia Submit manuscript

Abstract

A typical case of eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression is reported. The patient achieved complete remission after oral administration of all-trans retinoic acid without any exposure to cytotoxic agents. The facts strongly suggest that the genetic event occurred at the level of pluripotent stem cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Author information

Authors and Affiliations

  1. Division of Hematology, Department of Internal Medicine, Shanghai Chang-Zheng Hospital, China

    R-Q Yu & S-D Jiang

  2. Laboratory of Molecular Biology, Shanghai Institute of Hematology, China

    W Huang, S-J Chen & Z Chen

Authors
  1. R-Q Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S-J Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S-D Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Z Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yu, RQ., Huang, W., Chen, SJ. et al. A case of acute eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression and response to all-trans retinoic acid. Leukemia 11, 609–611 (1997). https://doi.org/10.1038/sj.leu.2400600

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.leu.2400600

  • Springer Nature Limited

Keywords

This article is cited by

Search

Navigation