Skip to main content
SpringerLink
Log in

Personalized care

Clinical staging of behavioral and psychological symptoms of dementia

  • Comment
  • Published:

From Nature Mental Health

View current issue Submit your manuscript

Clinical staging could be an actionable concept for behavioral and psychological symptoms of dementia (BPSD), providing clinicians with tools to navigate choices of treatment, acceptability of side effects and suitable care settings. This would pave the way for more research into tailored interventions that are much needed in high-stage BPSD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Steinberg, M. et al. Int. J. Geriatr. Psychiatry 23, 170–177 (2008).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Schoenmakers, B., Buntinx, F., Devroey, D., Van Casteren, V. & DeLepeleire, J. Int. J. Geriatr. Psychiatry 24, 523–531 (2009).

    Article  PubMed  Google Scholar 

  3. Beeri, M. S., Werner, P., Davidson, M. & Noy, S. Int. J. Geriatr. Psychiatry 17, 403–408 (2002).

    Article  PubMed  Google Scholar 

  4. Costa, N. et al. J. Am. Med. Dir. Assoc. 19, 95.e1–95.e10 (2018).

    Article  PubMed  Google Scholar 

  5. Brodaty, H., Draper, B. M. & Low, L. F. Med. J. Aust. 178, 231–234 (2003).

    Article  PubMed  Google Scholar 

  6. Martinez-Cao, C. et al. Transl. Psychiatry 12, 197 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Verduijn, J. et al. J. Clin. Psychiatry 76, 1200–1208 (2015).

    Article  PubMed  Google Scholar 

  8. Ouwens, M. A., Videler, A. C. & van Alphen, S. P. J. Clin. Gerontol. https://doi.org/10.1080/07317115.2022.2041143 (2022).

    Article  PubMed  Google Scholar 

  9. McGorry, P. D. & Hickie, I. B. Clinical Staging in Psychiatry: Making Diagnosis Work for Research and Treatment (Cambridge Univ. Press, 2019).

  10. Schneider, L. S., Dagerman, K. S. & Insel, P. JAMA 294, 1934–1943 (2005).

    Article  PubMed  Google Scholar 

  11. van der Linde, R. M., Stephan, B. C. M., Dening, T. & Brayne, C. Int. J. Methods Psychiatr. Res. 23, 69–98 (2014).

    Article  PubMed  PubMed Central  Google Scholar 

  12. Van Leeuwen, E. et al. Cochrane Database Syst. Rev. 3, CD007726 (2018).

    PubMed  Google Scholar 

Download references

Acknowledgements

The BPSD research of M.J.A.V.D.B. and L.V.d.B. is supported by the Funds Malou Malou, Perano, Georgette Paulus, JMJS Breugelmans and Gabrielle, François and Christian De Mesmaeker, Managed by the King Baudouin Foundation of Belgium (no. 2021-J1990130-222081) and the KU Leuven (C2M/23/053); M.J.A.V.D.B. and A.-M.P. are supported by the KU Leuven and the University of Melbourne (KU Leuven Global PhD partnerships); M.J.A.V.D.B. is supported by Klinische onderzoeks — en opleidingsraad (KOOR) of the University Hospitals Leuven; and M.V. is supported by Research Foundation Flanders (FWO) grant G0C0319N, KU Leuven Fund C24/18/095 and the Sequoia Fund for Research on Ageing and Mental Health. No funding source was directly involved in this manuscript.

Author information

Authors and Affiliations

  1. Department of Geriatric Psychiatry, University Psychiatric Center KU Leuven, Leuven, Belgium

    Maarten J. A. Van Den Bossche, Laura Van den Bulcke, Anne-Marie Peeters, Jan Van den Stock & Mathieu Vandenbulcke

  2. Center for Neuropsychiatry, Research Group Psychiatry, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium

    Maarten J. A. Van Den Bossche, Laura Van den Bulcke, Anne-Marie Peeters, Jan Van den Stock & Mathieu Vandenbulcke

  3. De Viersprong, Bergen op Zoom, The Netherlands

    Ann T. E. Van Vré

  4. Department of Electrical Engineering (ESAT), KU Leuven, Heverlee, Belgium

    Hannah Davidoff

  5. imec, Heverlee, Belgium

    Hannah Davidoff

Authors
  1. Maarten J. A. Van Den Bossche
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ann T. E. Van Vré
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Laura Van den Bulcke
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hannah Davidoff
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Anne-Marie Peeters
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jan Van den Stock
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Mathieu Vandenbulcke
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

The original draft was written by M.J.A.V.D.B., A.T.E.V.V., L.V.d.B. and M.V. The manuscript was reviewed and edited by M.J.A.V.D.B., A.T.E.V.V., L.V.d.B., H.D., A.-M.P., J.V.d.S. and M.V.

Corresponding author

Correspondence to Maarten J. A. Van Den Bossche.

Ethics declarations

Competing interests

The authors declare no competing interests.

Peer review

Peer review information

Nature Mental Health thanks the anonymous reviewers for their contribution to the peer review of this work.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Van Den Bossche, M.J.A., Van Vré, A.T.E., Van den Bulcke, L. et al. Clinical staging of behavioral and psychological symptoms of dementia. Nat. Mental Health 2, 3–5 (2024). https://doi.org/10.1038/s44220-023-00174-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s44220-023-00174-1

  • Springer Nature America, Inc.

Search

Navigation