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Body weight has varying effects on the risk of neurological and psychiatric disorders

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Inconsistent results have been obtained regarding the role of obesity and its related metabolic syndrome in neurological and psychiatric diseases. This systematic research using the UK Biobank demonstrates effects of body weight on the risk of several neurological and psychiatric disorders, and suggests that the higher risks may be partially explained by brain structure, food intake and inflammation.

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Fig. 1: Associations and underlying mechanisms of obesity-related measures on neurological and psychiatric disorder risk.

References

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This is a summary of: Wang, R.-Z. et al. Body weight in neurological and psychiatric disorders: a large prospective cohort study. Nat. Mental Health https://doi.org/10.1038/s44220-023-00158-1 (2024).

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Body weight has varying effects on the risk of neurological and psychiatric disorders. Nat. Mental Health 2, 15–16 (2024). https://doi.org/10.1038/s44220-023-00167-0

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