Skip to main content
SpringerLink
Log in

Biological aging — a new tool to detect cardiometabolic multimorbidity and mortality

  • Research Briefing
  • Published:

From Nature Cardiovascular Research

View current issue Submit your manuscript

Cardiometabolic multimorbidity — the coexistence of type 2 diabetes, ischemic heart disease or stroke — is a growing clinical and public health challenge. Accelerated biological aging, measured by clinical traits, provides innovative clues into subclinical prevention of cardiometabolic multimorbidity and mortality among older adults.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Associations of accelerated biological aging with the risks of FCMD, CMM and death using the multi-state model.

References

  1. The Emerging Risk Factors Collaboration. Association of cardiometabolic multimorbidity with mortality. JAMA 314, 52–60 (2015). This paper reports that CMM is a growing clinical and public health challenge.

    Article  PubMed Central  Google Scholar 

  2. Gao, X. et al. Accelerated biological aging and risk of depression and anxiety: evidence from 424,299 UK Biobank participants. Nat. Commun. 14, 2277 (2023). This paper reports that biological aging could predict depression and anxiety.

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  3. Gao, X., Huang, N., Guo, X. & Huang, T. Role of sleep quality in the acceleration of biological aging and its potential for preventive interaction on air pollution insults: findings from the UK Biobank cohort. Aging Cell 21, e13610 (2022). This paper reports the algorithm for estimating biological aging in UK Biobank participants and the joint effects of air pollution and sleep on biological aging.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. D’Agostino, R. B. et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 117, 743–753 (2008). This paper reports the algorithm of the FRS.

    Article  PubMed  Google Scholar 

  5. SCORE2 working group and ESC Cardiovascular risk collaboration. SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe. Eur. Heart J. 42, 2439–2454 (2021). This paper reports the algorithm of SCORE2.

    Article  Google Scholar 

Download references

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This is a summary of: Jiang, M. et al. Accelerated biological aging elevates the risk of cardiometabolic multimorbidity and mortality. Nat. Cardiovasc. Res. https://doi.org/10.1038/s44161-024-00438-8 (2024).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Biological aging — a new tool to detect cardiometabolic multimorbidity and mortality. Nat Cardiovasc Res 3, 267–268 (2024). https://doi.org/10.1038/s44161-024-00449-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s44161-024-00449-5

  • Springer Nature Limited

Search

Navigation