Acute depletion of meningeal lymphatic vessels impairs the clearance of cerebrospinal fluid and brain macromolecules. A new study by Antila et al. shows that amyloid pathology in Alzheimer’s disease is neither improved nor aggravated by genetic expansion or depletion of meningeal lymphatic vessels.
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Santisteban, M.M., Iadecola, C. A deeper dive into amyloid clearance by meningeal lymphatic vessels. Nat Cardiovasc Res 3, 407–409 (2024). https://doi.org/10.1038/s44161-024-00427-x
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DOI: https://doi.org/10.1038/s44161-024-00427-x
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