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Strained allenes for heterocycle difunctionalization

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Strained allenes in piperidines and tetrahydropyrans are used to generate highly-decorated heterocycles.

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Fig. 1: N-Heterocyclic allenes as key intermediates.

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  1. Department of Chemistry, University of Minnesota, Minneapolis, MN, USA

    Courtney C. Roberts

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  1. Courtney C. Roberts
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Correspondence to Courtney C. Roberts.

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Roberts, C.C. Strained allenes for heterocycle difunctionalization. Nat. Synth 3, 286–287 (2024). https://doi.org/10.1038/s44160-023-00455-8

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