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Electrochemical synthesis

Radical approach for enantioselective amination

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Enantioselective electrocatalysis is emerging as an increasingly versatile tool in organic synthesis. Now, by applying asymmetric Lewis acid catalysis with an elaborated ligand design, radical electrochemical amination is accomplished with full selectivity control.

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Fig. 1: Lewis acid-catalysed electrochemical radical amination as an innovative strategy for the synthesis of enantiomerically enriched α-amino carbonyl compounds.

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Authors and Affiliations

  1. Wöhler Research Institute for Sustainable Chemistry, Georg-August-Universität Göttingen, Göttingen, Germany

    Tristan von Münchow & Lutz Ackermann

Authors
  1. Tristan von Münchow
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  2. Lutz Ackermann
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Correspondence to Lutz Ackermann.

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The authors declare no competing interests.

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von Münchow, T., Ackermann, L. Radical approach for enantioselective amination. Nat. Synth 2, 1132–1133 (2023). https://doi.org/10.1038/s44160-023-00379-3

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