Suda and colleagues explore the enduring consequences of plasma membrane injury in budding yeast and mammalian cells. Their findings highlight that membrane damage induces irreversible cell-cycle arrest and premature cellular senescence, whereas upregulation of plasma membrane repair suppresses them.
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Sønder, S.L., Nylandsted, J. Plasma membrane damage causes cellular senescence. Nat Aging 4, 282–283 (2024). https://doi.org/10.1038/s43587-024-00584-5
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DOI: https://doi.org/10.1038/s43587-024-00584-5
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