Skip to main content
SpringerLink
Log in

BRAIN AGING

College education as a modulator of the aging brain

  • News & Views
  • Published:

From Nature Aging

View current issue Submit your manuscript

What makes some human brains more resilient to aging than others? In an Article in Nature Aging, Chan et al. provide evidence that brain connectomes in older adults are altered by a college education — an environmental factor that might be an advantageous modulator of brain reserve during aging.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Theoretical diagrams of network segregation and integration in the aging brain.

References

  1. Chan, M. Y. et al. Nat. Aging https://doi.org/10.1038/s43587-021-00125-4 (2021).

  2. Xu, W. et al. Mol. Neurobiol. 53, 3113–3123 (2016).

    Article  CAS  Google Scholar 

  3. Stern, Y. Neuropsychologia 47, 2015–2028 (2009).

    Article  Google Scholar 

  4. Bullmore, E. & Sporns, O. Nat. Rev. Neurosci. 10, 186–198 (2009).

    Article  CAS  Google Scholar 

  5. Yu, M., Sporns, O. & Saykin, A. J. Nat. Rev. Neurol 17, 545–563 (2021).

    Article  CAS  Google Scholar 

  6. Sepulcre, J. et al. Nat. Med. 24, 1910–1918 (2018).

    Article  CAS  Google Scholar 

  7. Guzmán-Vélez, E. et al. Preprint in https://doi.org/10.1101/2021.07.03.450933 (2021).

  8. Costumero, V. et al. Distance disintegration delineates the brain connectivity failure of Alzheimer’s disease. Neurobiol. Aging 88, 51–60 (2021).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Jorge Sepulcre

Authors
  1. Jorge Sepulcre
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jorge Sepulcre.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sepulcre, J. College education as a modulator of the aging brain. Nat Aging 1, 980–981 (2021). https://doi.org/10.1038/s43587-021-00131-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s43587-021-00131-6

  • Springer Nature America, Inc.

Search

Navigation