Skip to main content
SpringerLink
Log in

Cancer survivorship

Disparities, aging and childhood cancer

  • News & Views
  • Published:

From Nature Cancer

View current issue Submit your manuscript

A study reports that survivors of childhood cancer age faster than healthy controls and have increased risk of frailty and death; however, heterogeneity in outcomes was present, indicating inequities in risk. Knowledge about aging in high-risk groups holds the potential to identify interventions to improve survivorship outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Diagram of disparities in aging for childhood cancer survivors.

References

  1. Mandelblatt, J. S. et al. JAMA Oncol. 7, 1692–1699 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Campisi, J. Cell 120, 513–22 (2005).

    Article  CAS  PubMed  Google Scholar 

  3. Carroll, J. E., Bower, J. E. & Ganz, P. A. Nat. Rev. Clin. Oncol. 19, 173–187 (2022).

    Article  CAS  PubMed  Google Scholar 

  4. Ness, K. K. & Wogksch, M. D. Transl. Res. 221, 65–82 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Williams, A. L. M. et al. JAMA Netw. Open 6, E2344015 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Williams, D. R., Lawrence, J. A. & Davis, B. A. Ann. Rev. Publ. Health 40, 105–125 (2019).

    Article  Google Scholar 

  7. Farina, M. P., Kim, J. K. & Crimmins, E. M. J. Aging Health 35, 209–220 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Guida, J. L. Nat. Cancer https://doi.org/10.1038/s43018-024-00745-w (2024).

  9. Henderson, T. O., Ness, K. K. & Cohen, H. J. Am. Soc. Clin. Oncol. Educ. B. 34, e423–e430 (2014).

    Article  Google Scholar 

  10. Ness, K. K. et al. J. Clin. Oncol. 37, 10057–10057 (2019).

    Article  Google Scholar 

  11. Dale, W. et al. J. Clin. Oncol. 41, 4293–4312 (2023).

    Article  PubMed  Google Scholar 

  12. Bower, J. E. & Irwin, M. R. Brain. Behav. Immun. 51, 1–11 (2016).

    Article  PubMed  Google Scholar 

  13. Rentscher, K. E. et al. Cancer 129, 2741–2753 (2023).

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The authors were supported in part by National Institutes of Health (NIH) grants R01CA129769, R35CA197289, R35CA283926 and R21AG075008 (J.S.M.), R56AG068086 and R01AG082348 (J.E.C. and J.S.M.) and R01CA237535 (J.E.C.)

Author information

Authors and Affiliations

  1. Department of Psychiatry & Biobehavioral Sciences, Cousins Center for Psychoneuroimmunology, Jane and Terry Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles, Los Angeles, CA, USA

    Judith E. Carroll

  2. The Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA

    Judith E. Carroll

  3. Department of Oncology, Georgetown Lombardi Institute for Cancer and Aging Research, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA

    Jeanne S. Mandelblatt

Authors
  1. Judith E. Carroll
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jeanne S. Mandelblatt
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Judith E. Carroll.

Ethics declarations

Competing interests

The authors report no conflicts of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Carroll, J.E., Mandelblatt, J.S. Disparities, aging and childhood cancer. Nat Cancer 5, 695–696 (2024). https://doi.org/10.1038/s43018-024-00737-w

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s43018-024-00737-w

  • Springer Nature America, Inc.

Search

Navigation