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Harnessing oncology real-world data with AI

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Real-world data (RWD) and real-world evidence (RWE) from heterogeneous data sources has the potential to transform oncology research, especially when coupled with artificial intelligence (AI). We discuss the issues involved in primary data capture and post-hoc AI analysis and propose using AI to support the capture of primary RWD.

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References

  1. Raoof, S. & Kurzrock, R. Sci. Transl. Med. 14, eabn6911 (2022).

    Article  PubMed  Google Scholar 

  2. Swanson, K., Wu, E., Zhang, A., Alizadeh, A. A. & Zou, J. Cell 186, 1772–1791 (2023).

    Article  CAS  PubMed  Google Scholar 

  3. NIH National Library of Medicine. ClinicalTrials.gov https://clinicaltrials.gov/study/NCT04921553 (2021).

  4. Bartlett, V. L., Dhruva, S. S., Shah, N. D., Ryan, P. & Ross, J. S. JAMA Netw. Open 2, e1912869 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Soni, P. D. et al. J. Clin. Oncol. 37, 1209–1216 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Sieswerda, M. et al. JCO Clin. Cancer Inform. 7, e2200080 (2023).

    Article  PubMed  Google Scholar 

  7. Pearl, J. Causality 2nd edn (Cambridge Univ. Press, 2009).

  8. Wang, S. V. et al. JAMA 329, 1376–1385 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Wallach, J. D. et al. JAMA Netw. Open 4, e2133667 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Goodman, S. N., Schneeweiss, S. & Baiocchi, M. JAMA 317, 705–707 (2017).

    Article  PubMed  Google Scholar 

  11. Overhage, J. M. & McCallie, D. Physician Time Spent Using the Electronic Health Record During Outpatient Encounters: A Descriptive Study. Ann. Intern. Med. 172, 169–174 (2020).

    Article  PubMed  Google Scholar 

  12. Arndt, B. G. et al. Ann. Fam. Med. 15, 419–426 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  13. van Buchem, M. M. et al. npj Digit. Med. 4, 57 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  14. Nguyen, O. T. et al. JCO Clin. Cancer Inform. 7, e2200166 (2023).

    Article  PubMed  Google Scholar 

  15. Ciecierski-Holmes, T., Singh, R., Axt, M., Brenner, S. & Barteit, S. npj Digit. Med. 5, 162 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

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Correspondence to Giovanni Tonon.

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Mahon, P., Hall, G., Dekker, A. et al. Harnessing oncology real-world data with AI. Nat Cancer 4, 1627–1629 (2023). https://doi.org/10.1038/s43018-023-00689-7

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