The mechanisms regulating the progression of benign tumors to malignant carcinomas remain incompletely understood. A new study identifies the transcription factor NR2F2 as a specific regulator of this transition that plays critical roles in the maintenance of the malignant tumor state.
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Lim, H.Y.G., Barker, N. A key malignant switch in skin SCC. Nat Cancer 2, 1116–1118 (2021). https://doi.org/10.1038/s43018-021-00278-6
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DOI: https://doi.org/10.1038/s43018-021-00278-6
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