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GENERATIVE CHEMISTRY

Potent antimalarial drugs with validated activities

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From Nature Machine Intelligence

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Drug resistance in tropical diseases such as malaria requires constant improvement and development of new drugs. To find potential candidates, generative machine learning methods that can search for novel bioactive molecules can be employed.

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Fig. 1: Architecture of the junction-tree variational autoencoder (JT-VAE) model.

References

  1. Godinez, W. J. et al. Nat. Mach. Intell. https://doi.org/10.1038/s42256-022-00448-w (2022).

  2. Winkler, D. A. Front. Chem. 9, 39 (2021).

    Article  Google Scholar 

  3. Weininger, D. J. Chem. Inf. Comp. Sci. 28, 31–36 (1988).

    Article  Google Scholar 

  4. Jin, W., Barzilay, R. & Jaakkola, T. in Proc. of the 35th International Conference on Machine Learning 80 (eds Dy, J. & Krause, A.) 2323–2332 (PMLR, 2018).

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Authors and Affiliations

  1. Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Australia

    David A. Winkler

  2. Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia

    David A. Winkler

  3. School of Pharmacy, University of Nottingham, Nottingham, UK

    David A. Winkler

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  1. David A. Winkler
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Correspondence to David A. Winkler.

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The author declares no competing interests.

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Winkler, D.A. Potent antimalarial drugs with validated activities. Nat Mach Intell 4, 102–103 (2022). https://doi.org/10.1038/s42256-022-00451-1

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