The molecular underpinnings of the extensive cellular, morphological and functional plasticity of skeletal muscle in exercise training are poorly understood. We have now begun to unravel the complex epigenetic, transcriptional and proteomic networks that determine the muscle response to exercise in a manner depending on the training state.
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This is a summary of: Handschin, C. et al. Molecular control of endurance training adaptation in male mouse skeletal muscle. Nat. Metab. https://doi.org/10.1038/s42255-023-00891-y (2023).
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Complex regulatory processes control exercise adaptations of skeletal muscle. Nat Metab 5, 1856–1857 (2023). https://doi.org/10.1038/s42255-023-00894-9
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DOI: https://doi.org/10.1038/s42255-023-00894-9
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