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Association learning is impaired in insulin resistance and restored by liraglutide

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Sensory association learning is impaired in people with insulin resistance but can be restored following a one-time intervention with liraglutide. These findings provide ample evidence for metabolic signals as modulators of adaptive behaviour and suggest a potential role for GLP-1 receptor agonists in obesity management.

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Fig. 1: Differential effect of liraglutide on learning.

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This is a summary of: Hanssen, R. et al. Liraglutide restores impaired associative learning in individuals with obesity. Nat. Metab. https://doi.org/10.1038/s42255-023-00859-y (2023).

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Association learning is impaired in insulin resistance and restored by liraglutide. Nat Metab 5, 1262–1263 (2023). https://doi.org/10.1038/s42255-023-00870-3

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