By using a combination of transcriptomics, primary adipocyte culture and experimental medicine approaches, we identified the sodium-dependent serotonin transporter SERT as a novel regulator of human brown adipose tissue function.
References
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This is a summary of: Suchacki, K. J. et al. The serotonin transporter sustains human brown adipose tissue thermogenesis. Nat. Metab. https://doi.org/10.1038/s42255-023-00839-2 (2023).
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Inhibition of the serotonin transporter induces dysfunction of human brown adipose tissue. Nat Metab 5, 1264–1265 (2023). https://doi.org/10.1038/s42255-023-00851-6
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DOI: https://doi.org/10.1038/s42255-023-00851-6
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