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FRUCTOSE METABOLISM

Surprising findings in a ‘well-understood’ nutrient-assimilation pathway

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A study published in this issue of Nature Metabolism adds to the emerging evidence that the small intestine is an initial site of dietary fructose metabolism, especially at low fructose doses, thus decreasing exposure of the liver and the colonic microbiome to intact fructose.

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Fig. 1: Assimilation of dietary fructose involves interactions among the small intestine, liver and colonic microbiome in mice.

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Authors and Affiliations

  1. Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA, USA

    Marc Hellerstein

  2. Department of Medicine, University of California at San Francisco, San Francisco, CA, USA

    Marc Hellerstein

Authors
  1. Marc Hellerstein
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Correspondence to Marc Hellerstein.

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The author declares no competing interests.

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Hellerstein, M. Surprising findings in a ‘well-understood’ nutrient-assimilation pathway. Nat Metab 2, 561–563 (2020). https://doi.org/10.1038/s42255-020-0242-5

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