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Pancreatic islet secretion: gabbling via GABA

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A new study by Menegaz et al. in this issue of Nature Metabolism addresses fundamental questions on the acute regulation and role of GABA secretion in pancreatic islets.

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Fig. 1: Role of β-cell-derived GABA in the coordination of glucagon and insulin secretion in health and in type 2 diabetes.

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Authors and Affiliations

  1. Section of Cell Biology and Functional Genomics, Department of Metabolism, Reproduction and Digestion, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK

    Guy A. Rutter

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  1. Guy A. Rutter
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Correspondence to Guy A. Rutter.

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The author declares no competing interests.

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Rutter, G.A. Pancreatic islet secretion: gabbling via GABA. Nat Metab 1, 1032–1033 (2019). https://doi.org/10.1038/s42255-019-0142-8

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