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GENETICS

A CRISPR cut for messenger RNAs

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Lab Animal

To achieve knockdown rather than knockout of particular genes, a new paper demonstrates a CRISPR/Cas13 method that can efficiently edit mRNA in zebrafish, medaka, killifish, and mouse embryos.

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Authors and Affiliations

  1. Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK

    Rebecca Leech & Karuna Sampath

  2. MRC doctoral training programme, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK

    Rebecca Leech

  3. Centre for Mechanochemical Cell Biology, University of Warwick, Coventry, CV4 7AL, UK

    Karuna Sampath

  4. Centre for Early Life, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK

    Karuna Sampath

Authors
  1. Rebecca Leech
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  2. Karuna Sampath
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Correspondence to Karuna Sampath.

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The authors declare no competing interests.

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Leech, R., Sampath, K. A CRISPR cut for messenger RNAs. Lab Anim 49, 317–319 (2020). https://doi.org/10.1038/s41684-020-00661-3

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