Skip to main content
SpringerLink
Log in

AAA+ proteins: converging mechanisms, diverging functions

  • Meeting Report
  • Published:

From Nature Structural & Molecular Biology

View current issue Submit your manuscript

The second Keystone Symposium on AAA+ proteins, “AAA+ Proteins: From Atomic Structures to Organisms”, was held in Tahoe City, USA in January 2020. The program highlighted recent advances from structural, biochemical and cellular approaches that have extended our understanding of these important ATP-driven molecular machines.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Fei, X. et al. Elife 9, e52774 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Bard, J. A. M., Bashore, C., Dong, K. C. & Martin, A. Cell 177, 286–298.e15 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Ripstein, Z. A., Vahidi, S., Houry, W. A., Rubinstein, J. L. & Kay, L. E. Elife 9, e52158 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Durie, C. L. et al. Biophys. J. 116, 1856–1872 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Puchades, C. et al. Mol. Cell 75, 1073–1085.e6 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Lopez, K. E. et al. Nat. Struct. Mol. Biol. 27, 406–416 (2020).

    Article  CAS  PubMed  Google Scholar 

  7. Kotamarthi, H. C., Sauer, R. T. & Baker, T. A. Cell Rep. 30, 2644–2654.e3 (2020).

    Article  CAS  PubMed  Google Scholar 

  8. Islam, M. T., Ogura, T. & Esaki, M. Biochem. Biophys. Res. Commun. 523, 835–840 (2020).

    Article  CAS  PubMed  Google Scholar 

  9. Lo, Y.-H. et al. Nat. Commun. 10, 513 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Kardon, J. R., Moroco, J. A., Engen, J. R. & Baker, T. A. Elife 9, e54387 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Ye, Q. et al. Mol. Cell 77, 709–722.e7 (2020).

    Article  CAS  PubMed  Google Scholar 

  12. Jessop, M. et al. Commun. Biol. 3, 46 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Tondnevis, F. et al. Sci. Rep. 10, 1691 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Nirwan, N. et al. Nat. Commun. 10, 3058 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Demircioglu, F. E. et al. Nat. Commun. 10, 3262 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Sugihara, M. et al. J. Cell Biol. 218, 949–960 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Blythe, E. E., Gates, S. N., Deshaies, R. J. & Martin, A. Structure 27, 1820–1829.e4 (2019).

    Article  CAS  PubMed  Google Scholar 

  18. Tariq, A. et al. Cell Rep. 28, 2080–2095.e6 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Cupido, T., Pisa, R., Kelley, M. E. & Kapoor, T. M. Nat. Chem. Biol. 15, 444–452 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA

    Steven E. Glynn

  2. Department of Biochemistry, Brandeis University, Waltham, MA, USA

    Julia R. Kardon

  3. School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

    Oliver Mueller-Cajar

  4. Research Center for Natural Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea

    Carol Cho

Authors
  1. Steven E. Glynn
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Julia R. Kardon
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Oliver Mueller-Cajar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Carol Cho
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Steven E. Glynn, Julia R. Kardon, Oliver Mueller-Cajar or Carol Cho.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Glynn, S.E., Kardon, J.R., Mueller-Cajar, O. et al. AAA+ proteins: converging mechanisms, diverging functions. Nat Struct Mol Biol 27, 515–518 (2020). https://doi.org/10.1038/s41594-020-0444-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41594-020-0444-2

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation