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Leaky blood–brain barrier in long-COVID-associated brain fog

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Long COVID has remained an on-going public health issue in the years following the global pandemic. Here, we report blood–brain barrier disruption in patients with acute SARS-CoV-2 infection and brain fog, and patients presenting with long COVID, brain fog and cognitive decline, compared to those with long COVID without any neurological symptoms.

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Fig. 1: BBB disruption in patients with long COVID who present with brain fog.

References

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This is a summary of: Greene, C. et al. Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment. Nat. Neurosci. https://doi.org/10.1038/s41593-024-01576-9 (2024)

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Leaky blood–brain barrier in long-COVID-associated brain fog. Nat Neurosci 27, 395–396 (2024). https://doi.org/10.1038/s41593-024-01577-8

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