Skip to main content
SpringerLink
Log in

Robust adult neurogenesis in the primate hippocampus

  • Research Briefing
  • Published:

From Nature Neuroscience

View current issue Submit your manuscript

The extent to which neurogenesis occurs in adult primates is still controversial. Single-cell RNA sequencing, immunofluorescence staining, and ex vivo neurosphere culture experiments were performed using the adult macaque hippocampus. The results reveal robust adult neurogenesis in the dentate gyrus of the primate hippocampus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Adult neurogenesis in macaque hippocampus.

References

  1. Gonçalves, J. T., Schafer, S. T. & Gage, F. H. Adult neurogenesis in the hippocampus: from stem cells to behavior. Cell 167, 897–914 (2016). A Review article that presents all aspects of adult neurogenesis.

    Article  Google Scholar 

  2. Spalding, K. L. et al. Dynamics of hippocampal neurogenesis in adult humans. Cell 153, 1219–1227 (2013). Reports adult neurogenesis in humans using augmented 14C level.

    Article  CAS  PubMed Central  Google Scholar 

  3. Song, J., Olsen, R. H. J., Sun, J., Ming, G.-L. & Song, H. Neuronal circuitry mechanisms regulating adult mammalian neurogenesis. Cold Spring Harbor Persp. Biol. 8, a018937 (2016). A Review of the integration of adult newborn neurons into hippocampal circuits.

    Article  Google Scholar 

  4. Eriksson, P. S. et al. Neurogenesis in the adult human hippocampus. Nat. Med. 4, 1313–1317 (1998). Reports adult neurogenesis in humans for the first time.

    Article  CAS  Google Scholar 

  5. Hochgerner, H., Zeisel, A., Lönnerberg, P. & Linnarsson, S. Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing. Nat. Neurosci. 21, 290–299 (2018). Identifies all key neural precursor populations in scRNA-seq datasets from mice at various ages.

    Article  CAS  Google Scholar 

Download references

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This is a summary of: Hao, Z.-Z. et al. Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations. Nat. Neurosci. https://doi.org/10.1038/s41593-022-01073-x (2022).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Robust adult neurogenesis in the primate hippocampus. Nat Neurosci 25, 684–685 (2022). https://doi.org/10.1038/s41593-022-01075-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41593-022-01075-9

  • Springer Nature America, Inc.

Search

Navigation