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NEUROGENESIS

Neurogenesis right under your nose

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Postmortem studies have previously suggested that adult olfactory neurogenesis occurs in humans. In new research, Durante and colleagues obtained fresh tissue from healthy adult humans via endoscopic nasal surgery and used single-cell RNA sequencing (RNA-seq) to identify the entire neurogenic trajectory in the olfactory epithelium, confirming the existence of human olfactory neurogenesis.

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References

  1. Sorrells, S. F. et al. Nature 555, 377–381 (2018).

    Article  CAS  Google Scholar 

  2. Boldrini, M. et al. Cell Stem Cell 22, 589–599.e5 (2018).

    Article  CAS  Google Scholar 

  3. Kempermann, G. et al. Cell Stem Cell 23, 25–30 (2018).

    Article  CAS  Google Scholar 

  4. Durante, M. A. et al. Nat. Neurosci. https://doi.org/10.1038/s41593-020-0587-9 (2020).

    Article  PubMed  Google Scholar 

  5. Lim, D. A. & Alvarez-Buylla, A. Cold Spring Harb. Perspect. Biol. 8, a018820 (2016).

    Article  Google Scholar 

  6. Brann, J. H. & Firestein, S. J. Front. Neurosci. https://doi.org/10.3389/fnins.2014.00182 (2014).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Fletcher, R. B. et al. Cell Stem Cell 20, 817–830.e8 (2017).

    Article  CAS  Google Scholar 

  8. Olender, T. et al. BMC Genomics 17, 619 (2016).

    Article  Google Scholar 

  9. Chess, A., Simon, I., Cedar, H. & Axel, R. Cell 78, 823–834 (1994).

    Article  CAS  Google Scholar 

  10. Hahn, C.-G. et al. J. Comp. Neurol. 483, 154–163 (2005).

    Article  Google Scholar 

  11. Holbrook, E. H., Wu, E., Curry, W. T., Lin, D. T. & Schwob, J. E. Laryngoscope 121, 1687–1701 (2011).

    Article  CAS  Google Scholar 

  12. Bergmann, O. et al. Neuron 74, 634–639 (2012).

    Article  CAS  Google Scholar 

  13. Chen, M., Reed, R. R. & Lane, A. P. Cell Stem Cell 25, 501–513.e5 (2019).

    Article  CAS  Google Scholar 

  14. Alves, J., Petrosyan, A. & Magalhães, R. World J. Clin. Cases 2, 661–667 (2014).

    Article  Google Scholar 

  15. Scopa, C. et al. Cell Death Differ. https://doi.org/10.1038/s41418-019-0409-3 (2019).

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Sandrine Thuret.

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Berger, T., Lee, H. & Thuret, S. Neurogenesis right under your nose. Nat Neurosci 23, 297–298 (2020). https://doi.org/10.1038/s41593-020-0596-8

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