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Breaking up the StayGold dimer yields three photostable monomers

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The exceptionally photostable green fluorescent protein StayGold has been monomerized in different laboratories, which has generated three unique monomeric variants that will enable new imaging applications.

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Fig. 1: Compatibility of applications of fluorescent proteins with the aggregation state of the fluorescent protein that is used.

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Authors and Affiliations

  1. Swammerdam Institute for Life Sciences, Section of Molecular Cytology, van Leeuwenhoek Centre for Advanced Microscopy, University of Amsterdam, Amsterdam, the Netherlands

    Joachim Goedhart & Theodorus W. J. Gadella Jr

Authors
  1. Joachim Goedhart
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  2. Theodorus W. J. Gadella Jr
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Correspondence to Joachim Goedhart or Theodorus W. J. Gadella Jr.

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The authors declare no competing interests.

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Goedhart, J., Gadella, T.W.J. Breaking up the StayGold dimer yields three photostable monomers. Nat Methods 21, 558–559 (2024). https://doi.org/10.1038/s41592-024-02223-8

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