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LiMCA: Hi-C gets an RNA twist

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A multiomics method measures both the cellular three-dimensional genome and transcriptome at the single-cell level.

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Fig. 1: Side-by-side comparison between HiRES (left) and LiMCA (right).

References

  1. Wu, H. et al. Nat. Methods https://doi.org/10.1038/s41592-024-02239-0 (2024).

  2. Liu, Z. et al. Science 380, 1070–1076 (2023).

    Article  CAS  PubMed  Google Scholar 

  3. Tan, L., Li, Q. & Xie, X. S. Mol. Syst. Biol. 11, 844 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Hanchate, N. K. et al. Science https://doi.org/10.1126/science.aad2456 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Bashkirova, E. V. et al. eLife https://doi.org/10.7554/eLife.87445 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Markenscoff-Papadimitriou, E. et al. Cell 159, 543–557 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Monahan, K., Horta, A. & Lomvardas, S. Nature 565, 448–453 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Tan, L., Xing, D., Chang, C. H., Li, H. & Xie, X. S. Science 361, 924–928 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Tan, L., Xing, D., Daley, N. & Xie, X. S. Nat. Struct. Mol. Biol. 26, 297–307 (2019).

    Article  CAS  PubMed  Google Scholar 

  10. Pourmorady, A. D. et al. Nature https://doi.org/10.1038/s41586-023-06845-4 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA

    Jane Kawaoka & Stavros Lomvardas

  2. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA

    Jane Kawaoka & Stavros Lomvardas

Authors
  1. Jane Kawaoka
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  2. Stavros Lomvardas
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Correspondence to Stavros Lomvardas.

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The authors declare no competing interests.

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Kawaoka, J., Lomvardas, S. LiMCA: Hi-C gets an RNA twist. Nat Methods (2024). https://doi.org/10.1038/s41592-024-02205-w

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