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Imaging cleared tissues made easy

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A flexible open-top light-sheet microscope has been developed that can perform deep three-dimensional imaging on all clearing protocols with low and high optical resolution.

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Fig. 1: Simplified schematic of the optical layout of the hybrid open-top light-sheet microscope.

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Authors and Affiliations

  1. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

    Shigeaki Kanatani & Per Uhlén

Authors
  1. Shigeaki Kanatani
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  2. Per Uhlén
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Correspondence to Per Uhlén.

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The authors declare no competing interests.

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Kanatani, S., Uhlén, P. Imaging cleared tissues made easy. Nat Methods 19, 527–529 (2022). https://doi.org/10.1038/s41592-022-01424-3

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