Four independent research groups have used proximity ligation techniques to profile the in vivo mouse secretome.
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Wei, W. et al. Cell type-selective secretome profiling in vivo. Nat. Chem. Biol. 17, 326–334 (2021).
Liu, J., Jang, J. Y., Pirooznia, M., Liu, S. & Finkel, T. The secretome mouse provides a genetic platform to delineate tissue-specific in vivo secretion. Proc. Natl Acad. Sci. USA 118, e2005134118 (2021).
Droujinine, I. A. et al. Proteomics of protein trafficking by in vivo tissue-specific labeling. Nat. Commun. 12, 2382 (2021).
Kim, K.-E. et al. Dynamic tracking and identification of tissue-specific secretory proteins in the circulation of live mice. Nat. Commun. 12, 5204 (2021).
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Strack, R. Revealing the secretome. Nat Methods 18, 1273 (2021). https://doi.org/10.1038/s41592-021-01320-2
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DOI: https://doi.org/10.1038/s41592-021-01320-2
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